The results of this study showed that implementation of thromboprophylaxis protocols can reduce the incidence of venous thromboembolism. The mean age of patients was almost 48 years which was within the age range of people prone to venous thromboembolism (over 40 years of age).8
In addition, consistent with previous studies which have shown DVT to be more common among men,9
approximately 60% of our patients were male.
On the other hand, although previous studied have reported DVT to be more prevalent among more sedentary jobs, 9
the present study resulted in different findings. The job combination of our studied patients might have been affected by the type of patients who usually refer to Alzahra Hospital who are mostly of working and middle-class people. Other variables could have also affected job combination in our population.
Old age is one of the risk factors in patients with DVT.10
Some studies have indicated that if the pathophysiology of thromboembolism was fully understood, higher age could have also been an important factor in pulmonary thromboembolism.11
In addition to age, immobility and smoking were the most prevalent factors and were observed in 25% of patients. Venous thromboembolism is of high importance among hospitalized patients, surgery candidates, individuals with a sedentary lifestyle, and patients who use several anticoagulant drugs. Considering necessary cautions and preventive protocols would thus lower the incidence of the disease and its complications.12
Many studies have suggested the effects of a previous history of thromboembolism as one of the risk factors. It is thus one of the complications which is given high attention almost in all medical centers.13
In this study, almost half of the patients had more than one of the risk factors of venous thromboembolism. Therefore, determining the independent role of each factor is problematic and requires further comparative studies. However, the results indicated that there are many factors involved in the incidence of thromboembolism in Iranian society and there is usually more than one factor involved in this complication.
We also examined the incidence of venous thromboembolism before and after implementation of thromboprophylaxis. Out of 96 studied patients, 1 patient had low risk, 73 had medium risk, and 22 patients had high risk before the implementation of thromboprophylaxis. Out of 289 patients who were studied after the implementation of thromboprophylaxis, 35 patients had low risk, 230 had medium risk, and 24 had high risk. After implementation of the protocol, thromboprophylaxis had been prescribed for 11 patients with low risk, 200 patients with medium risk and 24 patients with high risk which indicates large attempt to reduce the incidence of venous thromboembolism after implementation of the protocol.
Our results showed that implementation of thromboprophylaxis protocol affected reduced venous thromboembolism. Therefore, conducting an analytical study is recommended to compare the incidence of venous thromboembolism and determine the effects of thrombolytic medications on the incidence of venous thromboembolism. The effects of common heparin thromboprophylaxis and low molecular weight heparin in the incidence of venous thromboembolism should be evaluated in hospitals throughout the province of Isfahan.