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Logo of bmccancBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Cancer
BMC Cancer. 2012; 12: 384.
Published online Sep 3, 2012. doi:  10.1186/1471-2407-12-384
PMCID: PMC3443003
Health-related quality of life among colorectal cancer patients in Malaysia: a study protocol
Bello Arkilla Magaji,corresponding author1 Foong Ming Moy,1 April Camilla Roslani,2,3 Ismail Sagap,6 Jasiah Zakaria,7 Jane M Blazeby,4,5 and Chee Wei Law2
1Julius Centre University of Malaya, Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
2Department of Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
3UMCRI (University of Malaya Cancer Research Institute), Kuala Lumpur, Malaysia
4Academic Unit of Surgical Research, School of Social and Community Medicine, University of Bristol, Bristol, UK
5Division of Surgery, Head & Neck, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
6Colorectal Surgery, UKM Medical Center, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Cheras, Kuala Lumpur, Malaysia
7Department of Surgery, Hospital Tuanku Jaafar, Jalan Rasah, 70300, Seremban, Negeri Sembilan, Malaysia
corresponding authorCorresponding author.
Bello Arkilla Magaji: drmagaji/at/; Foong Ming Moy: moyfm/at/; April Camilla Roslani: aprilroslani/at/; Ismail Sagap: drisagap/at/; Jasiah Zakaria: missjasiah65/at/; Jane M Blazeby: j.m.blazeby/at/; Chee Wei Law: cwlaw/at/
Received October 3, 2011; Accepted August 27, 2012.
Colorectal cancer is a major public health problem in Malaysia. However, it is also one of the most treatable cancers, resulting in significant numbers of survivors. Therefore, the impact of surviving treatment for colorectal cancer on health related quality of life is important for the patients, clinicians and policy makers, and may differ in different cultures and populations. The aim of this study was to validate the Malaysian versions of the European Organization for Research and Treatment of Cancer quality of life instruments among colorectal cancers patients.
This is a cross sectional multi centre study. Three hospitals were included, the University of Malaya Medical Centre, the Universiti Kebangsaan Malaysia Medical Centre and Hospital Tuanku Jaafar Seremban. Malaysian citizens and permanent residence were studied and demographic and clinical information obtained from hospital records. The European Organization for Research and Treatment of Cancer Quality of life Core 30, colorectal cancer CR29, and the colorectal cancer liver metastasis LMC 21 were used and an observer assessment of performance obtained with the Karnofsky Performance Scale. Questionnaires were translated into three most commonly spoken languages in Malaysia (Bahasa Malaysia, Chinese and Tamil), then administered, scored and analyzed following the developers’ guidelines. Ethical approval was obtained from the participating centres. Tests of reliability and validity were performed to examine the validity of these instruments.
The result of pilot testing shows that the use of the Malaysian versions of EORTC QLQ C30, CR29 instruments is feasible in our sample of colorectal cancer patients. Instructions for completion as well as questions were well understood except the questions on the overall quality of life, overall health status and sexual activity. Thus we anticipate obtaining good psychometric properties for the instruments at the end of the study.
Keywords: Colorectal cancer, Health related quality of life, Malaysia
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