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BMC Biol. 2012; 10: 75.
Published online Aug 21, 2012. doi:  10.1186/1741-7007-10-75
PMCID: PMC3424162
Different noses for different mice and men
Andreas Kellercorresponding author1
1The Rockefeller University, 1230 York Avenue, Box 63, New York, NY 10065, USA
corresponding authorCorresponding author.
Andreas Keller: andreas.keller/at/rockefeller.edu
Received August 20, 2012; Accepted August 20, 2012.
Abstract
Chemosensory receptor genes encode G protein-coupled receptors with which animals sense their chemical environment. The large number of chemosensory receptor genes in the genome and their extreme genetic variability pose unusual challenges for understanding their evolution and function. Two articles in BMC Genomics explore the genetic variation of chemosensory receptor gene repertoires in humans and mice and provide unparalleled insight into the causes and consequences of this variability.
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