Dr. Pilowsky reports financial support from NIMH, NIDA, and CDC. Dr. Alpert receives research support from Aspect Medical Systems, Eli Lilly, PamLab, and Pfizer, and he receives honoraria from Reed Medical Education and Belvoir Publishing. Dr. Trivedi has received research support from the Agency for Healthcare Research and Quality (AHRQ), Corcept Therapeutics, Cyberonics, Merck, National Alliance for Research in Schizophrenia and Depression, NIMH, National Institute on Drug Abuse, Novartis, Pharmacia & Upjohn, Predix EPIX Pharmaceuticals, Solvay Pharmaceuticals, and Targacept. He has received consulting and speaker fees from Abbott Laboratories, Abdi Ibrahim, Akzo (Organon Pharmaceuticals), AstraZeneca, Bristol-M yers Squibb, Cephalon, Evotec, Fabre Kramer Pharmaceuticals, Forest Pharmaceuticals, GlaxoSmithKline, Janssen Pharmaceutica Products, Johnson & Johnson PRD, Eli Lilly, Meade Johnson, Medtronic, Neuronetics, Otsuka Pharmaceuticals, Parke-Davis Pharmaceuticals, Pfizer, Sepracor, SHIRE Development, VantagePoint, and Wyeth-Ayerst Laboratories. Dr. Fava has received research support, advisory or consulting fees, and speaking or publishing fees from AstraZeneca, Bristol-Myers Squibb, Cephalon, Eli Lilly, Forest Pharmaceuticals, GlaxoSmithKline, Novartis AG, Organon Pharmaceuticals, and Pfizer. He has received research support and advisory or consulting fees from Abbott Laboratories, Alkermes, Aspect Medical Systems, BrainCells, CeNeRx BioPharma, Clinical Trials Solutions, Euthymics Bioscience, i3 Innovus/Ingenix, Johnson & Johnson PRD, Lorex Pharmaceuticals, PamLab, Pharmavite, Roche, RCT Logic, Sanofi-Aventis US, Solvay Pharmaceuticals, and Synthelabo. Dr. Fava has also received research support from BioResearch, Clintara, Covidien, EnVivo Pharmaceuticals, Ganeden Biotech, Icon Clinical Research, Lichtwer Pharma GmbH, NARSAD, NCCAM, NIDA, NIMH, Photothera, Shire, and Wyeth-Ayerst Laboratories. He has also received advisory or consulting fees from Affectis Pharmaceuticals AG, Amarin Pharma, Auspex Pharmaceuticals, Bayer AG, Best Practice Project Management, BioMarin Pharmaceuticals, Biovail Corporation, CNS Response, Compellis Pharmaceuticals, Cypress Pharmaceutical, DiagnoSearch Life Sciences, Dinippon Sumitomo Pharma, Dov Pharmaceuticals, Edgemont Pharmaceuticals, Eisai Inc., ePharmaSolutions, EPIX Pharmaceuticals, Fabre Kramer Pharmaceuticals, GenOmind, Grunenthal GmbH, Janssen Pharmaceutica, Jazz Pharmaceuticals, Knoll Pharmaceuticals, Labopharm, Lundbeck, MedAvante, Merck, MSI Methylation Sciences, Naurex, Neuronetics, NextWave Pharmaceuticals, Nutrition 21, Orexigen Therapeutics, Otsuka Pharmaceuticals, PharmaStar, PharmoRx Therapeutics, Precision Human Biolaboratory, Prexa Pharmaceuticals, Puretech Ventures, PsychoGenics, Psylin Neurosciences, Rexahn Pharmaceuticals, Ridge Diagnostics, Sepracor, Servier Laboratories, Schering-Plough Corporation, Somaxon Pharmaceuticals, Somerset Pharmaceuticals, Sunovion Pharmaceuticals, Takeda Pharmaceutical Company Limited, Tal Medical, Tetragenex Pharmaceuticals, TransForm Pharmaceuticals, Transcept Pharmaceuticals, and Vanda Pharmaceuticals. Dr. Fava has also received speaking or publishing fees from Adamed, Advanced Meeting Partners, American Psychiatric Association, American Society of Clinical Psychopharmacology, Belvoir Media Group, Boehringer Ingelheim GmbH, CME Institute/Physicians Postgraduate Press, Imedex, MGH Psychiatry Academy/Primedia, MGH Psychiatry Academy/Reed Elsevier, PharmaStar, United BioSource, and Wyeth-Ayerst Laboratories. Dr. Fava has equity holdings in Compellis and receives royalty, patent, or other income from a patent for SPCD and patent application for a combination of azapirones and bupropion in major depressive disorder, copyright royalties for the MGH CPFQ, SFI, ATRQ, DESS, and SAFER. He has a patent for research and licensing of SPCD with RCT Logic; Lippincott, Williams & Wilkins. Dr. Rush has received consultant fees from Advanced Neuromodulation Systems, AstraZeneca, Best Practice Project Management, Brain Resource, Bristol-Myers Squibb/Otsuka, Cyberonics, Forest Pharmaceuticals, Gerson Lehrman Group, Glaxo-SmithKline, Jazz Pharmaceuticals, Magellan Health Services, Merck & Company, Neuronetics, Novartis Pharmaceuticals, Ono Pharmaceuticals, Organon, Otsuka Pharmaceuticals, Pamlab, Pfizer, The University of Michigan, Transcept Pharmaceuticals, Urban Institute and Wyeth Ayerst; speaking fees from Cyberonics, Forest Laboratories, GlaxoSmithKline, and Otsuka; royalties from Guilford Publications, Healthcare Technology Systems, and The University of Texas Southwestern Medical Center; and research support from NIMH and the Stanley Medical Research Institute. He has owned shares of stock in Pfizer. Dr. Wisniewski has received consultant fees from Cyberonics, ImaRx Therapeutics, Bristol-Myers Squibb Company, Organon, Case-Western University, Singapore Clinical Research Institute, Dey Pharmaceuticals, Venebio, and Dey. The remaining authors report no financial relationships with commercial interests.
Supported by NIMH grant R01MH063852 (Dr. Weissman, principal investigator) and by an NIMH contract (N01 MH90003) (Dr. Rush, principal investigator). Dr. Garber was supported in part by an Independent Scientist Award K02 MH66249 from NIMH.