Intravesical knotting of catheters have been reported more commonly in males than females, and more commonly in neonates and children than adults [
2]. Intravesical knotting has been reported not only in catheters left for bladder drainage, but also after brief maneuvers such as clean intermittent catheterization, and cystourethrography [
3,
4,
5]. This is the first instance that this complication has been encountered following posterior sagittal anorectoplasty.
Although knotting of urethral catheters is rare, removal represents significant morbidity, such as general anesthesia, radiation exposure during fluoroscopy, and transient hematuria [
1]. Potential for further complications such as stricture formation also needs to be considered. Knotted urinary catheters may also jeopardize delicate surgical reconstructions [
3,
6]. Unfortunately, many doctor colleagues and nursing staff are unaware of this problem or its proper management. A telephone survey of 24 tertiary- care Emergency Departments in Canada revealed that none of them were aware of catheter knotting and 22 had no protocol established for safe catheterization [
1].
Several hypothetical explanations have been offered for the knotting of catheters. The tendency of a catheter to knot probably depends on its flexibility, smaller diameter and redundancy within the bladder. The probable mechanism involves an extra length of catheter coiling around itself and then the catheter end looping through these coils [
4]. The coils tighten cinching down in a knot when counter traction is applied to remove the catheter. If the diameter of this knot exceeds that of urethra the catheter gets stuck. Bladder spasm has been also been attributed as a risk factor [
7]. Water-current generated by the flow of urine around the catheter may also play a role in the genesis of catheter knotting [
2]. Raveenthiran suggested that the catheters slender than 10 Fr, over-distended bladder and insertion of excessive length (greater than 10 cm beyond bladder neck) of catheters must be considered as risk factors for catheter knotting [
2].
Several techniques have been described to retrieve the knotted catheter. They include sustained traction under anesthesia, unraveling the knot using a guide-wire through the catheter under fluoroscopy, endoscopic retrieval and suprapubic cystotomy [
4,
7,
8,
9]. Guide-wire manipulation is useful only at the early ‘open-loop stage’ of knot formation when the knot is not tight enough [
8] and succeeded in one of our cases. Sustained traction also worked once, but such a manipulation with or without urethral dilatation carries the risk of urethral damage. Moreover, this technique is not useful when the knot is bulky or when two catheters knot together [
2]. Suprapubic cystotomy has been known as a simple, safe and cost-effective method of retrieving knotted bladder catheters [
10], though in the modern era, this could be replaced by vesicoscopy.
The attention should be directed towards prevention of this complication by careful selection of the catheters and gaining better understanding of urethral anatomy and safe insertion lengths. The insertion lengths of 6 cm in a male newborn and 5 cm in a female newborn have been recommended [
10]. In extremely premature babies with birth weight of &<750 grams the insertion length of &<2.5 cm in girls and &<5 cm in boys is recommended [
10]. It is also equally important to secure the catheter well in order to prevent inadvertent advancement of the catheter into the bladder [
1].