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Logo of bmcpsycBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Psychiatry
 
BMC Psychiatry. 2012; 12: 83.
Published online 2012 July 19. doi:  10.1186/1471-244X-12-83
PMCID: PMC3413583

Risk factors for suicide behaviors in the observational schizophrenia outpatient health outcomes (SOHO) study

Abstract

Background

To identify risk factors for suicide using data from a large, 3-year, multinational follow-up study of schizophrenia (SOHO study).

Methods

Baseline characteristics of 8,871 adult patients with schizophrenia were included in a logistic regression post-hoc analysis comparing patients who attempted and/or committed suicide during the study with those who did not.

Results

384 (4.3%) patients attempted or committed suicide. Completed suicides were 27 (0.3%). The significant risk factors for suicide behaviors were previous suicidality, depressive symptoms, prolactin-related adverse events, male gender and history of hospitalization for schizophrenia.

Conclusions

In view of the observational design of the study and the post-hoc nature of the analysis, the identified risk factors should be confirmed by ad-hoc specifically designed studies.

Keywords: Suicide, Schizophrenia, Observational study

Articles from BMC Psychiatry are provided here courtesy of BioMed Central