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Logo of anclinmicBioMed CentralBiomed Central Web Sitesearchsubmit a manuscriptregisterthis articleAnnals of Clinical Microbiology and Antimicrobials
 
Ann Clin Microbiol Antimicrob. 2012; 11: 14.
Published online May 18, 2012. doi:  10.1186/1476-0711-11-14
PMCID: PMC3410774
Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis
Serdal Korkmaz,corresponding author1,4 Nazif Elaldi,2 Mansur Kayatas,1 Mehmet Sencan,1 and Esin Yildiz3
1Department of Internal Medicine, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
2Department of Infectious Diseases and Clinical Bacteriology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
3Department of Pathology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
4Department of Internal Medicine, Cumhuriyet University, Faculty of Medicine, 58140, Sivas, Turkey
corresponding authorCorresponding author.
Serdal Korkmaz: srdlkorkmaz/at/mynet.com; Nazif Elaldi: nelaldi61/at/yahoo.com; Mansur Kayatas: mansurkay/at/yahoo.com; Mehmet Sencan: msencan/at/cumhuriyet.edu.tr; Esin Yildiz: esinyldz/at/cumhuriyet.edu.tr
Received January 4, 2012; Accepted May 18, 2012.
Abstract
Q fever is a worldwide zoonotic infection that caused by Coxiella burnetii, a strict intracellular bacterium. It may be manifested by some of the autoimmune events and is classified into acute and chronic forms. The most frequent clinical manifestation of acute form is a self-limited febrile illness which is associated with severe headache, muscle ache, arthralgia and cough. Meningoencephalitis, thyroiditis, pericarditis, myocarditis, mesenteric lymphadenopathy, hemolytic anemia, and nephritis are rare manifestations. Here we present a case of acute Q fever together with Coombs’ positive autoimmune hemolytic anemia (AIHA) and tubulointerstitial nephritis treated with chlarithromycin, steroids and hemodialysis. Clinicians should be aware of such rare manifestations of the disease.
Keywords: Q fever, Pneumonia, Autoimmune hemolytic anemia, Tubulointerstitial nephritis
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