PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

Logo of frontoncoLink to Publisher's site
 
From:
Published online 2012 August 2. doi: 10.3389/fonc.2012.00087

Table 1

ER-Associated Cell Death in Mammalian and Yeast Cells.

ER functionOrganismTriggers of cell death (select list)ER proteins involved
Protein translocation and foldingMammalianProtein aggregationIRE1α
Ischemia reperfusionATF6
Beta-mercaptoethanol (BME)PERK
TunicamycinBI
Dithiothreitol (DTT)Grp78/BiP
YeastHeat shockIre1p
Beta-mercaptoethanol (BME)Bxi1p
TunicamycinKar2p/BiP
Dithiothreitol (DTT)
Lipid synthesisMammalianElevated free fatty acids (FFA)IRE1α
ATF6
PERK
YeastElevated saturated fatty acidsIre1p
(SFA) inositol starvationCnx1p
Calcium dynamicsMammalianThapsigarginPERK
Calcium overloadSERCA
Grp78/BiP
YeastCalcium starvationPmr1p
Calcium chelators