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Logo of bmcpediBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Pediatrics
 
From:
Published online 2012 April 4. doi: 10.1186/1471-2431-12-43

Table 7

Review of the literature on nasal intermittent positive pressure ventilation (NIPPV) vs. nasal continuous positive airway pressure (NCPAP) for preventing extubation failure

Study author, YearInclusion criteriaIntervention
group
Control
group
Primary outcomeResults
Barrington
2001
BW < 1,251 grams
PNA < 6 wks
NSIMV
(N = 27)
NCPAP
(N = 27)
Extubation failure at 72 hours4/27 (14%) vs. 12/27 (44%) in the NSIMV vs. NCPAP (P < 0.05)
Median age at extubation (range)
3 (1, 29) vs. 3 (1, 40) days

Friedlich 1999BW 500-1,500 gramsNP-SIMV (N = 22)NCPAP (N = 19)Respiratory failure at
48 hours
1/22 (5%) vs.7/19 (37%) in the NP-SIMV vs. NCPAP group
(P = 0.016)
Median age at extubation (range) 18.5 (1, 120) vs. 21(1, 54) days

Khalaf 2001GA ≤ 34 weeks, RDSSNIPPV (N = 34)NCPAP (N = 30)Remained extubated at 72 hours32/34 (94%) vs. 18/30 (60%) in the SNIPPV vs. NCPAP group
(P < 0.01)
Median age at extubation (range) 4 (1, 83) vs. 2.5 (1, 106) days

Morretti
2008
BW < 1,251 grams
PNA < 14 days
NFSIPPV (N = 32)NCPAP
(N = 31)
Remained extubated at 72 hours30/32 (94%) vs. 19/31(61%) in the
NFSIPPV vs. NCPAP (P < 0.01)
Median age at extubation (range)
4 (1, 14) vs. 6 (1, 14) days

*BW = Birth weight, CPAP = Continuous positive airway pressure, GA = Gestational age, NCPAP = Nasal continuous positive airway pressure, NSIMV = Nasal synchronized intermittent mandatory ventilation, NFSIPPV = Nasal flow synchronized intermittent positive pressure ventilation, PNA = Post natal age, SNIPPV = Synchronized nasal intermittent positive pressure ventilation