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Autoimmune Dis. 2012; 2012: 290898.
Published online 2012 July 2. doi:  10.1155/2012/290898
PMCID: PMC3395333

Ocular Manifestations of Systemic Lupus Erythematosus: A Review of the Literature

Abstract

About one-third of patients suffering from systemic lupus erythematosus have ocular manifestations. The most common manifestation is keratoconjunctivitis sicca. The most vision threatening are retinal vasculitis and optic neuritis/neuropathy. Prompt diagnosis and treatment of eye disease is paramount as they are often associated with high levels of systemic inflammation and end-organ damage. Initial management with high-dose oral or IV corticosteroids is often necessary. Multiple “steroid-sparing” treatment options exist with the most recently studied being biologic agents.


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