PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

Logo of ohtasLink to Publisher's site
 
From:
Published online 2009 September 1.

Table 8:

ESS reported in RCTs comparing MAS to CPAP for the treatment of OSA
StudyTreatmentBaseline
ESS
Follow-up
ESS
Mean
difference
between
baseline and
follow-up
Mean
difference
between MAS
and Placebo
Clinical
significance
Hoekema et al.
2008 (16-19)*
MAS (n=51)12.9 SD 5.66.9 SD 5.56.0
NR
1.0
P=.53
Yes
Parallel arm study
(N=103)
CPAP
(n=52)
14.2 SD 5.65.9 SD 4.88.3
NR
Yes
Lam et al.
2007 (20)
MAS (n=34)12.0 SD 8.39.0 SD 8.33.0
P<.001
2.0
P<.05
Yes
Parallel arm study
(N=101)
CPAP
(n=34)
12.0 SD 8.37.0 SD 8.35.0
P<.001
Yes
Barnes et al.
2004 (10)
MAS10.7 SD 3.69.2 SD 3.61.5
P<.001
0
P=NS
Yes
Crossover study
(N=80)
CPAP10.7 SD 3.69.2 SD 3.61.5
P<.001
Yes
Engleman et al.
2002(21)
MAS13.0 SD 412.0 SD 51.0
NR
4.0
P<.001
No
Crossover study
(N=48)
CPAP15.0 SD 38.0 SD 57.0
NR
Yes
Randerath et al.
2002 (22)
MASNot reported
Crossover study
(N=20)
CPAP
Tan et al.
2002 (23)
MAS13.4 SD 4.69.0 SD 5.14.4
P<.001
0.9
P=NS
Yes
Crossover study
(N=24)
CPAP13.4 SD 4.68.1 SD 4.15.3
P<.001
Yes
Ferguson et al.
1997 (24)
MAS10.3 SD 3.14.7 SD 2.65.6
P<.005
−0.4
P=NS
Yes
Crossover study
(N=24)
CPAP11.0 SD 3.85.1 SD 3.35.9
P<.05
Yes
Ferguson et al.
1996 (25)
MASNot reported
Crossover study
(N=27)
CPAP
Note: AHI, apnea hypopnea index; CPAP, continuous positive airway pressure; ESS, Epworth Sleepiness Scale; MAS, mandibular advancement splint; NR, not reported; SD, standard deviation
*The same group of authors published results for a RCT between 2007-2008.