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Published online 2012 May 17. doi: 10.1371/journal.pcbi.1002514

Figure 4

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Function similarity (all ontologies combined) of corresponding 1[ratio]1 orthologs among human, mouse, and an outgroup.

The outgroups are (A) D. melanogaster, (B) S. cervisiae, and (C) E. coli. Strikingly, function is maintained among 1[ratio]1 orthologs over all evolutionary ranges considered here. Histograms represent sample density partitioned for each homology type, and error bars represent the 95% confidence interval around the mean.

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