This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Based on the yeast interaction data of Duan et al., hypergeometric and resampling-based P-values were computed to assess the extent to which certain functional groups colocalize. The height of each bar indicates enrichment or depletion of observed interchromosomal interactions relative to the percent (black line) of all possible interactions that were observed at a false discovery rate below 0.01. Above each bar, the resampling-based P-value is reported (without correction for multiple testing), and an asterisk indicates that the hypergeometric P-value was below 0.01 after Bonferroni correction. Additional information about the fourteen sets of functional elements can be found in Duan et al. (3).