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Nucleic Acids Res. 1992 November 25; 20(22): 6106.
PMCID: PMC334485

Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes.

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Selected References

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  • Hoeffler JP, Meyer TE, Yun Y, Jameson JL, Habener JF. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science. 1988 Dec 9;242(4884):1430–1433. [PubMed]
  • Hoeffler JP, Meyer TE, Waeber G, Habener JF. Multiple adenosine 3',5'-cyclic [corrected] monophosphate response element DNA-binding proteins generated by gene diversification and alternative exon splicing. Mol Endocrinol. 1990 Jun;4(6):920–930. [PubMed]
  • Gonzalez GA, Yamamoto KK, Fischer WH, Karr D, Menzel P, Biggs W, 3rd, Vale WW, Montminy MR. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature. 1989 Feb 23;337(6209):749–752. [PubMed]
  • Foulkes NS, Mellström B, Benusiglio E, Sassone-Corsi P. Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature. 1992 Jan 2;355(6355):80–84. [PubMed]
  • Ruppert S, Cole TJ, Boshart M, Schmid E, Schütz G. Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J. 1992 Apr;11(4):1503–1512. [PubMed]
  • Lee CQ, Yun YD, Hoeffler JP, Habener JF. Cyclic-AMP-responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J. 1990 Dec;9(13):4455–4465. [PubMed]
  • Yun YD, Dumoulin M, Habener JF. DNA-binding and dimerization domains of adenosine 3',5'- cyclic monophosphate-responsive protein CREB reside in the carboxyl-terminal 66 amino acids. Mol Endocrinol. 1990 Jun;4(6):931–939. [PubMed]
  • Waeber G, Meyer TE, LeSieur M, Hermann HL, Gérard N, Habener JF. Developmental stage-specific expression of cyclic adenosine 3',5'-monophosphate response element-binding protein CREB during spermatogenesis involves alternative exon splicing. Mol Endocrinol. 1991 Oct;5(10):1418–1430. [PubMed]

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