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Logo of bmccancBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Cancer
BMC Cancer. 2012; 12: 135.
Published online 2012 April 3. doi:  10.1186/1471-2407-12-135
PMCID: PMC3342888

The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?


Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor. As our understanding of tumorigenesis is increasing the relevance of immunobiology will become apparent.

Keywords: Tumor infiltrating lymphocytes, Cancer, Immunobiology

Articles from BMC Cancer are provided here courtesy of BioMed Central