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Anc Sci Life. 2011 Apr-Jun; 30(4): 100–103.
PMCID: PMC3336264
Anti inflammatory activity of Myrica nagi Linn. Bark
Tejaa Patel,* Ashvin Dudhpejiya, and Navin Sheath
Department of Pharmaceutical Sciences, Saurashtra University, Rajkot, Gujarat, India
*Corresponding Author
Abstract
The present study evaluated the anti inflammatory activity of ethyl acetate and aqueous extracts of bark of M. nagi using carrageenan and histamine induced rat paw edema. Adult Wistar albino rats were subjected to carrageenan and histamine induced rat paw edema tests. In carrageenan induced rat paw edema the effects of ethyl acetate and aqueous extract at 100 and 200 mg/kg showed % inhibition of edema 27% and 22% respectively than the standard drug aspirin (28%). These ethyl acetate and aqueous extract extracts also showed % inhibition of edema 25% and 18% respectively than the standard drug (27%) when rats challenged with histamine induced rat paw edema. Future research should focus on the identification and the anti inflammatory activity of the constituents from this plant.
Keywords: Anti inflammatory activity, Myrica nagi, Carrageenan, Histamine, Ethyl acetate extract, Aqueous extract
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