Expression of interleukin 1 receptor (IL-1R) and its negative regulators during endotoxin-induced uveitis. (A) depicts the protein expression of IL-1R and the indicated negative regulators of IL-1 signalling in eye tissue in response to intraocular injection of 250 ng LPS versus saline at 5 h after injection. Shown are three individual wild-type (WT) mice (a total of nine individual mice were examined). (B) IL-1Ra concentrations in eye homogenates of WT mice were analysed by ELISA to compare responses to intraocular injection of 250 ng LPS vs saline at 5 h after injection. *p<0.05 for comparison between LPS and saline (n=8 mice/treatment).