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Amoebiasis is a problem in northern India. In Ayurveda several herbal drugs are mentioned, to be used for controlling the amatisara (amoebiasis) but none of the drug are found having potent effect to iradicate the disease. In ancient literature kutaj (Holarrhena antidysentrica) is mentioned in commonest was for controlling the disease this plant is prevalently found in Himalayan and vindhaya area. It is very effective for relieving amoebiasis. By seeing its theuraptic importance we have tried to standardize the compound in whole with special reference to kutaj. The detail composition and method of preparation of drug with its therapeutic effect will be narrated during the time of workshop.