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Logo of agdisAging and DiseaseAboutEditorial BoardSubmissionAchieves

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Immunosenesence of the aging immune system. The adult immune system becomes less responsive to vaccination, and less able to cope with infectious disease with age. Multiple arms of the immune system have been shown to develop age-related defects resulting in the loss or decreased effectiveness of key protective functions. Development of improved influenza vaccines for older adults must overcome these age related defects to improve protection of this high risk population.

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