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Logo of bmcgastBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Gastroenterology
 
BMC Gastroenterol. 2012; 12: 17.
Published online Feb 22, 2012. doi:  10.1186/1471-230X-12-17
PMCID: PMC3310780
Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions: a pilot feasibility trial
Takafumi Omori,1 Yoshio Kamiya,1 Tomomitsu Tahara,corresponding author1 Tomoyuki Shibata,1 Masakatsu Nakamura,2 Joh Yonemura,1 Masaaki Okubo,1 Daisuke Yoshioka,1 Takamitsu Ishizuka,1 Naoko Maruyama,1 Toshiaki Kamano,1 Hiroshi Fujita,1 Yoshihito Nakagawa,1 Mitsuo Nagasaka,1 Masami Iwata,1 Tomiyasu Arisawa,2 and Ichiro Hirata1
1Department of Gastroenterology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan
2Department of Gastroenterology, Kanazawa Medical University, 1-1 Daigaku, Uchinadamachi, Ishikawa 920-0293, Japan
corresponding authorCorresponding author.
Takafumi Omori: takafumi1981/at/gmail.com; Yoshio Kamiya: angelyopi/at/fujita-hu.ac.jp; Tomomitsu Tahara: tomomiccyu/at/yahoo.co.jp; Tomoyuki Shibata: shibat03/at/fujita-hu.ac.jp; Masakatsu Nakamura: qchannakamura1111/at/yahoo.co.jp; Joh Yonemura: yonejoe517517/at/yahoo.co.jp; Masaaki Okubo: masa2050309/at/yahoo.co.jp; Daisuke Yoshioka: daikomi2002/at/yahoo.co.jp; Takamitsu Ishizuka: kuroioyaji0005/at/yahoo.co.jp; Naoko Maruyama: naokomaruyama-gi/at/umin.ac.jp; Toshiaki Kamano: tkamano/at/fujita-hu.ac.jp; Hiroshi Fujita: hirofish/at/fujita-hu.ac.jp; Yoshihito Nakagawa: yo-hi/at/fujita-hu.ac.jp; Mitsuo Nagasaka: mnagasa/at/bg8.so-net.ne.jp; Masami Iwata: masami/at/fujita-hu.ac.jp; Tomiyasu Arisawa: tarisawa/at/kanazawa-med.ac.jp; Ichiro Hirata: ihirata/at/fujita-hu.ac.jp
Received June 26, 2011; Accepted February 22, 2012.
Abstract
Background
Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.
Methods
Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.
Results
Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).
Conclusion
Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.
Keywords: NBI, Stomach, Magnifying endoscopy, Polypoid lesions, Gastric cancer
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