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Oncomine analysis of Spp1 mRNA expression in human HCC. Box-plot diagrams were analyzed to compare the Spp1 mRNA levels in normal liver tissue with that in HCC using the Oncomine dataset from studies reported by Mas et al. (**p-value < 0.01), Chen et al. (**p-value < 0.01), and Wurmbach et al. (**p-value < 0.01). The vertical axis represents the log2 median value. The upper (75%) and lower (25%) quartiles are represented by the upper and lower borders of the boxes, respectively.