PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

Logo of bmcmedgenoBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Medical Genomics
 
From:
Published online 2012 January 27. doi: 10.1186/1755-8794-5-5

Figure 1

An external file that holds a picture, illustration, etc.
Object name is 1755-8794-5-5-1.jpg

Validation of a mouse model of CCl4-induced early-stage liver fibrosis. (A) The effect of CCl4 treatment on enzymatic activities of serum Alt and Ast. The vertical axis represents each enzymatic activity (U/I) plus the standard deviation (**p-value < 0.01, n = 3-4). (B) The effect of CCl4 treatment on mRNA levels of collagen-related genes. mRNA levels of ECM-related genes, such as αSma, Col1a2, and Timp1, were determined by qPCR. Cyclophilin was used as the normalization control. The vertical axes represent the relative mRNA quantity plus the standard deviation (**p-value < 0.01, n = 3-4). (C) Histological changes induced by CCl4 in mouse livers. Paraffin-fixed liver section stained with H&E, MT, and Sirius-red (original magnification ×400).

Images in this article

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
Click on the image to see a larger version.