The CARDIoGRAM and C4D GWAS consortia facilitated collaboration. GWA studies in the C4D Consortium made use of controls from the National Blood Service and the 1958 British Birth Cohort and of data generated by the Wellcome Trust Case-Control Consortium (full list of the investigators who contributed to the generation of the data available from www.wtccc.org.uk
We are grateful to the following investigators who contributed to the MTHFR Studies Collaborative Group: Unpublished datasets (ordered by number of cases): deCODE, H Holm, U Thorsteinsdottir, S Gretarsdottir, JR Gulcher, G Thorgeirsson, K Andersen, K Stefansson, deCODE, Rejkavik, Iceland; ISIS collaborative group (S Parish, DA Bennett, R Clarke, R Peto, P Sleight, R Collins), CTSU, Oxford, UK; PROCARDIS, JC Hopewell, R Clarke, R Collins, H Watkins, University of Oxford, UK; PROMIS, D Saleheen, J Danesh, University of Cambridge, UK and A Rasheed, M Zaidi, P Frossard, N Shah, M Samuel, Center for Non-Communicable Diseases, Pakistan; OACIS, T Tanaka, K Ozaki, RIKEN Center for Genomic Medicine, Yokohama, Japan and H Sato, Y Sakata, I Komuro, Osaka University, Suita, Japan; INTERHEART, SS Anand, S Yusuf, McMaster University, Hamilton, Canada and JC Engert, McGill University, Montreal, Canada; LOLIPOP, J Chambers, J Kooner, Imperial College, London, UK; HPS, JC Hopewell, S Parish, R Clarke, R Peto, J Armitage, R Collins, University of Oxford, UK; BHF-Family Heart Study, NJ Samani, PS Braund, CP Nelson, University of Leicester, UK and AS Hall, A Balmforth, SG Ball, University of Leeds, UK; Blood-omics (Germany LURIC), ME Kleber, MM Hoffmann, Freiburg; WA März, P Bugert, Heidelberg, B Winkelmann, Frankfurt, BO Böhm, Ulm, and WH Ouwehand, Cambridge, UK; Blood-omics (The Netherlands), S Sivapalaratnam, JJ Kastelein, MD Trip, CR Bezzina, University of Amsterdam and W Ouwehand, Cambridge, UK; Yamada (GAG-U and Aichi), Y Yamada, Mie University, Tsu, Japan; EPIC (The Netherlands), CC Elbers, NC Onland-Moret, F Bauer, YT van der Schouw, WM Verschuren, JM de Boer, C Wijmenga, MH Hofker, PIW de Bakker, University of Utrecht; UCP (The Netherlands), BJM Peters, AH Maitland-van der Zee, A de Boer, OH Klungel, DE Grobbee, Utrecht; Ottawa Heart Study, AFR Stewart, R Roberts, R McPherson, L Chen, GA Wells, University of Ottawa, Canada; PennCath, MM Reilly, M Li, l Qu, DJ Rader, University of Pennsylvania School of Medicine, Philadelphia, USA; MONICA-KORA, B Thorand, T Illig, A Peters, Helmholtz Zentrum, German Center for Environmental Health, München, W Koenig, University of Ulm, Germany; ADVANCE, TL Assimes, S Fortmann, C Iribarren, Stanford University, Palo Alto, California, USA.
Published studies that provided individual data (ordered by first author of publication):
R Abbate, R Marcucci, University of Florence, Italy; JL Anderson, JS Zebrack, University of Utah, Salt Lake City, USA; D Ardissino, FM Merlini, AB Bonomi, Hemophilia and Thrombosis Center, Milan, Italy; PAL Ashfield-Watt, ZE Clark, University of Wales, Cardiff, UK; FM van Bockxmeer, L Brownrigg, Royal Perth Hospital, Australia; J Chambers, JS Kooner, Hammersmith Hospital, London, UK; C Ferrer-Antunes, A Palmeiro, Hospitais da Universidade de Coimbra, Portugal; N Fernandez-Arcas, A Reyes-Engel, University of Malaga, Spain; ARIC, AR Folsom, University of Minnesota, Minneapolis, USA; EAS, FGR Fowkes, AJ Lee, University of Edinburgh, UK; JM Gaziano, VA Boston Healthcare System, Massachusetts, USA; D Gemmati, GL Scapoli, University of Ferrara, Italy; J Genest, Royal Victoria Hospital, Montreal and R Rozen, Montreal Children's Hospital, Quebec, Canada; D Girelli, R Corrocher, GB Rossi, Verona, Italy; COMAC, R Meleady, IM Graham, Adelaide and Meath Hospital, Dublin, Ireland; S Gulec, Medical School of Ankara University, Turkey; PN Hopkins, Cardiovascular Genetics, Salt Lake City, Utah, USA; A Inbal, U Selighson, Sheba Medical Center, Tel Hashomer, Israel; JW Jukema, Leiden University Medical Center, The Netherlands; P Litynsky, University Children's Hospital, Basel, Switzerland; REGRESS, LAJ Kluijtmans, University Medical Center, Nijmegen, The Netherlands; V Kozich, B Janosikova, Charles University, Prague, Czech Republic; PHS, J Ma, MJ Stampfer, Channing Laboratory, Boston, Massachusetts, USA; MR Malinow, Oregon Regional Primate Research Center, Beaverton, Oregon, USA; C Meisel, K Stangl, Universitätsklinikum Charite, Berlin, Germany; H Morita, Harvard Medical School, Boston, Massachusetts, USA; R Nagai, University of Tokyo, Japan; K Nakai, Iwate Medical University, Morioka, Japan; CCHS, BG Nordestgaard, J Zacho, Copenhagen University Hospital, Denmark; HPFS, EB Rimm, Harvard School of Public Health, Boston, Massachusetts, USA; NJ Samani, University of Leicester, UK; SM Schwartz, DS Siscovick, University of Seattle, Washington, USA; NFHS, JS Silberberg, John Hunter Hospital, Newcastle, Australia; A Szczeklik, BT Domagala, Jagiellonian University School of Medicine, Krakow, Poland; BC Tanis, FM Rosendaal, Leiden University Medical Center, The Netherlands; AM Thogersen, TK Nilsson, Umea University Hospital, Sweden; L Todesco, University of Basel, Switzerland; SL Tokgozoglu, Hacettepe University, Ankara, Turkey; MY Tsai, NQ Hanson, University of Minnesota, Minneapolis, USA; BJ Verhoeff, MD Trip, Academic Medical Center, Amsterdam, The Netherlands; K Yamakawa-Kobayashi, H Hamaguchi, University of Tsukuba, Japan.