Palliative care focuses on complex pain and symptom management, communication about care goals, alignment of treatments with patient values and preferences, transitional planning, and support for the family. Increasingly, this type of care is seen as an essential component of comprehensive care for patients with critical illness, including those receiving aggressive intensive care therapies (1
). Although prior literature has illuminated why palliative care should be integrated in the intensive care unit (ICU) and which aspects of ICU palliative care could be improved, guidance on how this might be effectively accomplished in practice remains limited. This article focuses on practical approaches to ICU palliative care, which extend across a spectrum that is defined at either end by models we refer to as “consultative” and “integrative.” We describe key features of these models, which can be combined; discuss their advantages and disadvantages; provide examples of initiatives using the different models; address the process of choosing an appropriate model; and review outcomes of effective integration of palliative care in the ICU setting.
This article does not report a research study involving human or animal subjects. As such, no approval was required from the Institutional Review Board.
Main Models for Palliative Care Integration in the ICU
There are two main models for ICU–palliative care integration. One, the “consultative model,” focuses on increasing the involvement and effectiveness of palliative care consultants in the care of ICU patients and their families, particularly those patients identified as at highest risk for poor outcomes (e.g., death in the hospital or early postdischarge period; severe functional and/or cognitive impairment). The second approach, the “integrative model,” seeks to embed palliative care principles and interventions into daily practice by the ICU team for all patients and families facing critical illness. These models are shown in and described more fully subsequently.
Figure 1 This figure illustrates the two main models for integration of palliative care in the intensive care unit (ICU). The “consultative model” focuses on increasing the involvement and effectiveness of palliative care consultants in the care (more ...) Consultative Model: Palliative Care Consultation in the ICU
Expert palliative care through a consultation service is currently available at the majority of US hospitals, including >75% of large hospitals, all Veterans’ Affairs medical centers, and an increasing number of smaller and community-based hospitals (5
). The National Consensus Project for Quality Palliative Care (www.nationalconsensusproject.org
), a consortium of the nation’s leading palliative care organizations, has developed and updated Clinical Practice Guidelines for Quality Palliative Care to describe the core elements of clinical palliative care programs (6
); these standards were adopted by the National Quality Forum (www.qualityforum.org
) within its Framework and Preferred Practices for Palliative and Hospice Care (7
) and recently operationalized by the Center to Advance Palliative Care (www.capc.org
). Qualified physicians can become certified by the American Board of Internal Medicine as subspecialists in hospice and palliative medicine through any of ten cosponsoring boards in the American Board of Medical Specialties. Palliative care nurses are certified by the National Board for Certification of Hospice and Palliative Nurses (www.nbchpn.org
Over two decades ago, clinicians at Detroit Receiving Hospital described efficiencies and savings in critical care resource use measured by reduction of Therapeutic Intervention Severity Scores, bed costs, and lengths of ICU and hospital stay with referrals of ICU patients who were “not expected to survive hospitalization” by the primary team to a “Comprehensive Supportive Care Team” (9
). This specialized team, including an advanced practice nurse as the main provider in collaboration with a rotating attending physician, accepted primary care responsibility for patients, who were moved to general medical/surgical wards for implementation of the supportive care plan (9
). Subsequent reports from the same institution and others describe additional initiatives involving proactive referrals by ICUs to the hospital’s palliative care consultation service (11
). Features of these initiatives are summarized in . Typically, the consultative model for integrating palliative care in the ICU addresses a subset of ICU patients at highest risk for poor outcomes rather than all patients in the ICU. Many successful initiatives using this consultative model have identified clinical “triggers” for palliative care consultation. Even if consultation is triggered only for specific groups of ICU patients, however, the “ripple effect” resulting from an increased presence of palliative care consultants in the ICU may stimulate referrals for other patients and help to enculturate palliative care within the usual care of the ICU.
Palliative care consultation model for the intensive care unit
Triggers for palliative care consultation can include baseline patient characteristics (e.g., pre-existing functional dependence, age >80 yrs, advanced-stage malignancy), selected acute diagnoses (e.g., global cerebral ischemia after cardiac arrest, prolonged dysfunction of multiple organs), and/or healthcare use criteria (e.g., specified duration of ICU treatment, referral for tracheotomy or gastrostomy, decision to forgo life-sustaining therapy such as renal replacement). For pediatric ICUs, extreme prematurity, severe traumatic brain injury, and Trisomy 13 are illustrative trigger criteria. For some ICUs, the trigger is the judgment of the critical care physician that a poor outcome is likely or the failure of initial ICU efforts to address palliative care needs of the patient or family. Triggers can be used to initiate a full palliative care consultation or a preliminary review with a palliative care clinician to determine whether such a consultation is needed (13
). In some ICUs, a palliative care clinician joins ICU rounds on a regular basis to help with timely identification of patients and families who could benefit from expert palliative care input (12
The palliative care professionals who provide consultative service vary by institution. In some ICUs, the service is provided by a single consultant, often an advanced practice nurse, whereas in others, consultations are performed by an interdisciplinary team of palliative care clinicians, including a physician, nurse, social worker, psychologist, and/or chaplain. A child life specialist may join a pediatric palliative care consultation team. The National Consensus Project Clinical Practice Guidelines for Quality Palliative Care and the Consensus Recommendations on Hospital Palliative Care Programs from the Center to Advance Palliative Care have established standards for palliative care services, including their composition and availability (6
). Some hospitals do not yet have palliative care consultation services but do have clinical ethics consultants who can assist in meeting certain palliative care needs of ICU patients and families such as discussion of appropriate care goals and resolution of conflict over such goals (15
Scope of consultation
Using a synthesis of empirical evidence and expert consensus, the Robert Wood Johnson Foundation Critical Care End-of-Life Peer Workgroup identified seven key domains of ICU palliative care: 1) patient- and family-centered decision making; 2) communication within the team and with patients and families; 3) continuity of care; 4) emotional and practical support for patients and families; 5) symptom management and comfort care; 6) spiritual support for patients and families; and 7) emotional and organizational support for ICU clinicians (17
). These domains map to those addressed by the National Consensus Project for Quality Palliative Care in its Clinical Practice Guidelines (6
), which are premised on the “expectation … that palliative care services delivered by all healthcare professionals within the scope of their disciplines and care settings will rise to the level of ‘best practice’ to meet the needs of their patients” (p 8). A comprehensive palliative care consultation includes all of these domains. In the ICU, however, palliative care consultants may be asked to focus on a narrower range of issues; most common among these are goal setting, withdrawal of unwanted life-prolonging therapies, do not resuscitate designation, conflict resolution, and transitional planning. Expertise in palliative care does not substitute for primary intensive care in any area but may be helpful to the critical care team for complex or refractory problems across the domains of palliative care, just as expert input enhances primary intensive care in cardiology, nephrology, infectious diseases, or other relevant fields. Depending on the care model of the ICU and the relationship between the critical care and palliative care teams, responsibility for implementation of consultants’ recommendations may remain solely with the ICU team or be shared with or delegated to the palliative care consultants (e.g., palliative care consultants might join or lead ICU family meetings to establish goals of care).
Integrative Model: Integration of Palliative Care in Daily ICU Practice
Because rates of mortality and other unfavorable outcomes are high in ICUs and virtually all critically ill patients and their families have palliative needs, many critical care professionals and others believe that the critical care team itself should integrate palliative care principles into daily ICU practice. An initiative starting from this premise emphasizes internal efforts to enhance systems of care as well as ICU clinicians’ knowledge and skills in palliative care; provides examples. Changes in the ICU’s routine typically affect all patients but can be focused on specific subgroups, like those targeted by triggering criteria for palliative care consultation (examples in ).
ICU integration of palliative care in daily practice: Examples of initiatives
Knowledge and skills
Although many ICU clinicians have experience in addressing certain palliative care needs of patients and families, few have been specifically trained to provide this type of care. Such training is valuable, however, for clinical challenges like managing multiple symptoms in the context of organ failure and adverse effects from first-line analgesic therapy, and communicating with families about limitation of intensive care therapies. In addition, these areas are explicitly included among competencies for critical care physicians that were recommended by a Task Force representing the Society of Critical Care Medicine, American College of Chest Physicians, American Thoracic Society, American Board of Internal Medicine, and the Association of Pulmonary and Critical Care Medicine Program Directors (16
). Thus, educational efforts targeted to physicians, nurses, and other members of the critical care team are a key component of initiatives to strengthen internal capability for ICU palliative care. Some ICUs have developed or accessed palliative care specialists and other experts in their own institution as educators. Critical care professionals can also attend national programs with relevant content such as the End of Life Nursing Education Consortium (ELNEC)–Critical Care training program (18
), the Initiative for Pediatric Palliative Care program (19
), and postgraduate courses at annual meetings of societies representing critical care professionals. A team of intensivists and palliative care experts has created and piloted a new Critical Care Communication skills program (“C-3”) for fellows training in critical care (20
); curricular modules used in this course will be available online (21
). An ongoing initiative in Veterans’ Integrated Service Network 3 includes a novel program of communication skills training for ICU staff nurses to enhance their participation in interdisciplinary meetings with families of critically ill patients.
Systems of care
Dramatic successes in ICU patient safety have been achieved by recent ICU initiatives emphasizing systematization of work processes to achieve the targeted objectives (22
). This approach is applicable to palliative care integration by ICUs, which also requires design and implementation of effective systems to support best clinical practice. Like the checklists and other technical supports that have been essential to reduction of catheter-related bloodstream infections, simple tools can facilitate assessment and management of palliative needs of ICU patients and families. Some ICUs have implemented comprehensive systems incorporating multiple tools to ensure integration of palliative care. For example, a trauma ICU implemented a multifaceted intervention including palliative care assessment of all patients within 24 hrs followed by a family meeting within 72 hrs and, for patients receiving care focused exclusively on comfort, a palliative care order set and clinical practice guidelines for ventilator withdrawal (23
). Other ICUs have developed a standardized order set for withdrawal of mechanical ventilation in patients who are not expected to survive (“palliative” or “terminal” extubation) (24
). A Family Meeting Planner, Guide for Families in booklet form, and Documentation Template comprise a tool kit that can be used along with other strategies to improve the frequency and quality of ICU family meetings (25
). The new IPAL-ICU Project, supported by the National Institutes of Health and the Center to Advance Palliative Care, is designed to serve as a comprehensive, online repository of practical resources for improving palliative care in the ICU, including prototypes of selected tools that can be adapted and refined for use by specific ICUs (21
Several initiatives have focused on improving the ICU’s performance of specific palliative care processes. For example, Lilly et al (27
) used an “intensive communication intervention” involving pro-active family meetings within 72 hrs of ICU admission for patients for whom the ICU attending physician predicted a length of ICU stay >5 days, risk of death >25%, or potentially irreversible change in function precluding eventual return to home; meetings included the attending intensivist, house staff, ICU nurse, family, and patient whenever possible. A before–after comparison showed a 1-day reduction in median length of ICU stay for patients receiving this intervention and shorter time to consensus about appropriate goals of care (27
). A new “bundle” of ICU–palliative care process measures provided the basis for a large-scale performance improvement initiative by ICUs in the Transformation of the ICU Project by the Voluntary Hospital Association, Inc (28
) and for an ongoing initiative by ICUs in Veterans’ Integrated Service Network 3 (25
). Processes measured by this tool include identification of the patient’s surrogate medical decision maker and resuscitation status; offers of emotional, practical, and spiritual support; and an interdisciplinary family meeting to discuss the patient’s condition, prognosis, and goals of care (29
) (). Performance of these care processes is evaluated by medical record documentation and is reviewed with ICU clinicians as feedback for performance improvement.
Intensive Care Unit Palliative Care Processes in the Voluntary Hospital Association, Inc “Care and Communication Bundle”a
Pros and Cons of the Main Models
Both models we describe for assimilating palliative care in the ICU have advantages and disadvantages, which we summarize in . Given the challenges inherent in the individual models, a combined approach using elements from both models may be optimal and has been described for a medical ICU (12
) and a surgical ICU (30
). This hybrid approach requires availability of palliative care consultants, commitment by the critical care team to strengthening internal capability for palliative care delivery, and a willingness to collaborate.
Pros and cons of the main models for integrating palliative care in the intensive care unit
Choosing an Approach
Choosing an overall approach from among these models should be one of the earliest steps in planning an ICU–palliative care initiative. This process will entail a careful and realistic assessment of available resources, attitudes of key stakeholders, structural aspects of ICU care, and patterns of local practice in the ICU and hospital. For an initiative based mainly on the consultative model, the palliative care service must have sufficient staffing to meet increased demand from the ICU, knowledge and skill to address unique needs of critically ill patients and their families, and a commitment to support structures, processes, and plans of care established by the critical care team. This approach also requires a reasonable level of receptivity on the part of ICU clinicians to input from palliative care experts. Often, the critical care nurses are the earliest team members to embrace palliative care consultation, with intensive care physicians taking longer to acknowledge the need for or value of expert consultation in this area; in time, the nurses’ enthusiasm usually spreads across disciplines, especially if an ICU physician with leadership responsibility provides support and direction. One way to evaluate and enhance the readiness of both the palliative care and ICU teams for collaboration is to invite participation by palliative care consultants in ICU patient care rounds, for example, several days each week, at least for a trial period. Although time-consuming for the consultants, their presence on rounds provides a valuable opportunity to demonstrate the feasibility, acceptability, and benefits of regular collaboration and to build mutual trust for use of the consultative model in an ongoing initiative. This trust is enhanced by acknowledgment from palliative care consultants of the value of life-sustaining treatments for appropriate patients with severe illness, even some with underlying chronic and life-limiting illness. It is also strengthened by education of ICU clinicians about the value of early integration of palliative care during critical illness, even when intensive care therapies are to continue.
Success of the integrative model will require a strong and sustained commitment from ICU physicians and nurses to strengthen their knowledge, skills, and systems for incorporating palliative care into daily practice. If a social worker, psychologist, or chaplain is assigned or accessible to the unit, this individual can help to facilitate palliative care integration. In addition, this approach depends on a supportive culture in which all disciplines on the critical care team endorse a central role for palliative care principles within regular ICU practice. In planning successful initiatives to improve patient safety, interdisciplinary discussions in which participants identify possible barriers to implementation and suggest strategies for overcoming barriers have been helpful in building a culture that is conducive to improvements in care (31
). Presentation of baseline data related to palliative care performance (e.g., data on adherence to important processes of care such as clinician meetings with families; on family psychological well-being; or on relevant aspects of resource use) highlights opportunities for improvement. A meeting of this kind may similarly help those planning a palliative care initiative both to evaluate and to expand the ICU’s capabilities for implementation using an integrative approach.
In the end, most ICUs will choose a combined approach. The appropriate “balance” between activities by palliative care consultants and those by clinicians on the critical care team needs to be determined for each specific ICU, even within a single institution, and may shift over time depending on a range of factors, including the results of early efforts, changes in resources available from the palliative care service, and/or increasing internal capability of the ICU for palliative care delivery. A project team representing key stakeholders in an ICU–palliative care initiative (e.g., critical care and palliative care physician and nurse leaders; members of other relevant disciplines such as social work and chaplaincy; hospital leadership) is in the best position to set this balance and adjust it as needed over time.
Impact of Palliative Care Integration in the ICU
A well-structured initiative to enhance palliative care in the ICU can provide important benefits for patients, families, and providers, as summarized in . Several studies have shown that palliative care consultation for patients meeting trigger criteria and proactive communication interventions by palliative care or ethics consultants or by the ICU team are associated with reductions in use of non-beneficial ICU treatments, length of ICU stay, and/or conflict over care goals (11
). The primary mechanism for efficiencies in use is earlier clarification of patients’ preferences and consensus in decision making, allowing timely implementation of an appropriate plan of care. This explains how ICUs have achieved these favorable outcomes without increasing ICU mortality. The use of a brochure about the ICU increased levels of satisfaction and comprehension of relevant medical information among families (34
) and an intervention combining proactive clinician meetings and a brochure for families of patients dying in the ICU reduced family anxiety, depression, and posttraumatic stress disorder 3 months after the patient’s death (35
). Systematic assessment improved ratings of pain, increased therapeutic adjustments of analgesics (escalation and de-escalation), and decreased the duration of mechanical ventilation (36
). Further research is needed to evaluate impact on other outcomes including job satisfaction of intensive care clinicians.
Benefits of integrating palliative care in the intensive care unit