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Nucleic Acids Res. Dec 10, 1983; 11(23): 8197–8203.
PMCID: PMC326575
Molecular cloning of the human gastrin gene.
K Kato, Y Hayashizaki, Y Takahashi, S Himeno, and K Matsubara
Abstract
A genomic clone that contains the human gastrin gene was isolated from a human gene library. Restriction endonuclease mapping and DNA sequencing analysis revealed that this gene is about 0.7 kb long, and has an intron. The intron is located at a position that separates the coding region into the peptide region essential for biological activities of gastrin and the non-essential, N-terminal peptide region.
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