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Logo of advvirolAdvances in Virology
 
From:
Published online 2011 November 14. doi: 10.1155/2012/798526

Table 1

Overview of the composition of bispecific adapters used to reroute viruses for oncolytic purposes.

Adaptor protein moiety binding toTargeting demonstrated for
VirionCell
Antibody (scFv or Fab)Antibody (scFv or Fab)Adenovirus
Adenoassociated virus
Coronavirus
Antibody (scFv or Fab)Ligand peptideAdenovirus
Paramyxovirus

Soluble/pseudo receptorAntibody (scFv or Fab)Adenovirus
Herpesvirus
Coronavirus
Soluble/pseudo receptorLigand peptideAdenovirus
Coronavirus

PolymerAntibody (scFv or Fab)Adenovirus
PolymerLigand peptideAdenovirus