Search tips
Search criteria 


Logo of thijTexas Heart Institute JournalSee also Cardiovascular Diseases Journal in PMCSubscribeSubmissionsTHI Journal Website
Tex Heart Inst J. 1990; 17(2): 99–102.
PMCID: PMC326462

Use of Absorbable Sutures in Canine Carotid Arteries


To study the functional and microstructural characteristics of polydioxanone sutures in vascular surgery, we created 48 vascular anastomoses in the right and left common carotid arteries of 24 mongrel dogs. In each animal, polydioxanone sutures were used in 1 carotid artery, and polypropylene sutures were used in the contralateral carotid artery. Twelve groups of 2 animals each were then formed. The 1st group was observed for 1 month, the 2nd for 2 months, the 3rd for 3 months, and so on until the 12th group, which was observed for 12 months. At the end of each observation period, reoperation was undertaken to evaluate the vascular anastomoses by means of angiography and microscopy. The polypropylene anastomoses showed a marked deformity, with tissue retraction and a foreign body reaction. In contrast, the polydioxanone anastomoses exhibited satisfactory healing, without deformity, and were well tolerated histologically. We believe that polydioxanone may be a useful, alternative vascular suture material. (Texas Heart Institute Journal 1990;17:99-102)

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (848K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Dardik H, Dardik I, Katz AR, Smith RB, Schwibner BH, Laufman H. A new absorbable synthetic suture in growing and adult primary vascular anastomoses: morphologic study. Surgery. 1970 Dec;68(6):1112–1121. [PubMed]
  • Rodeheaver GT, Powell TA, Thacker JG, Edlich RF. Mechanical performance of monofilament synthetic absorbable sutures. Am J Surg. 1987 Nov;154(5):544–547. [PubMed]
  • Sugimura S, Starr A. Cardiopulmonary bypass in infants under four months of age. J Thorac Cardiovasc Surg. 1977 Jun;73(6):894–899. [PubMed]
  • Myers JL, Waldhausen JA, Pae WE, Jr, Abt AB, Prophet GA, Pierce WS. Vascular anastomoses in growing vessels: the use of absorbable sutures. Ann Thorac Surg. 1982 Nov;34(5):529–537. [PubMed]
  • MOSS AJ, ADAMS FH, O'LOUGHLIN BJ, DIXON WJ. The growth of the normal aorta and of the anastomotic site in infants following surgical resection of coarctation of the aorta. Circulation. 1959 Mar;19(3):338–349. [PubMed]
  • Newfeld EA, Paul MM, Muster AJ, Idriss FS. Pulmonary vascular disease in complete transposition of the great arteries: a study of 200 patients. Am J Cardiol. 1974 Jul;34(1):75–82. [PubMed]
  • Lakier JB, Stanger P, Heymann MA, HoffmaN JI, Rudolph AM. Early onset of pulmonary vascular obstruction in patients with aortopulmonary transposition and intact ventricular septum. Circulation. 1975 May;51(5):875–880. [PubMed]
  • Yacoub MH, Bernhard A, Radley-Smith R, Lange P, Sievers H, Heintzen P. Supravalvular pulmonary stenosis after anatomic correction of transposition of the great arteries: causes and prevention. Circulation. 1982 Aug;66(2 Pt 2):I193–I197. [PubMed]
  • Verschuere I, Francois K, De Roose J, Berzsenyi G, Derom F. Polydioxanone suture material in growing vascular anastomoses. Experimental study. J Thorac Cardiovasc Surg. 1985 Nov;90(5):765–770. [PubMed]
  • Tuchmann A, Dinstl K. Polydioxanone in vascular surgery. First experience with an absorbable suture in femoro-popliteal bypass. J Cardiovasc Surg (Torino) 1984 May-Jun;25(3):225–229. [PubMed]
  • Myers JL, Campbell DB, Waldhausen JA. The use of absorbable monofilament polydioxanone suture in pediatric cardiovascular operations. J Thorac Cardiovasc Surg. 1986 Oct;92(4):771–775. [PubMed]
  • Gillatt DA, Corfield AP, May RE, Bartolo DC, Leaper DJ. Polydioxanone suture in the gastrointestinal tract. Ann R Coll Surg Engl. 1987 Mar;69(2):54–56. [PMC free article] [PubMed]
  • el-Mahrouky A, McElhaney J, Bartone FF, King L. In vitro comparison of the properties of polydioxanone, polyglycolic acid and catgut sutures in sterile and infected urine. J Urol. 1987 Oct;138(4):913–915. [PubMed]
  • Schoetz DJ, Jr, Coller JA, Veidenheimer MC. Closure of abdominal wounds with polydioxanone. A prospective study. Arch Surg. 1988 Jan;123(1):72–74. [PubMed]
  • Cameron AE, Parker CJ, Field ES, Gray RC, Wyatt AP. A randomised comparison of polydioxanone (PDS) and polypropylene (Prolene) for abdominal wound closure. Ann R Coll Surg Engl. 1987 May;69(3):113–115. [PMC free article] [PubMed]
  • Bartholomew RS. PDS (polydioxanone suture): a new synthetic absorbable suture in cataract surgery. A preliminary study. Ophthalmologica. 1981;183(2):81–85. [PubMed]
  • Töns C, Armbrecht J, Bircks W. The use of synthetic absorbable suture materials (polyglycolic acid and polydioxanone) in the low pressure circulatory system of growing organisms. Thorac Cardiovasc Surg. 1986 Apr;34(2):128–131. [PubMed]
  • Katz AR, Mukherjee DP, Kaganov AL, Gordon S. A new synthetic monofilament absorbable suture made from polytrimethylene carbonate. Surg Gynecol Obstet. 1985 Sep;161(3):213–222. [PubMed]
  • Steen S, Andersson L, Löwenhielm P, Stridbeck H, Walther B, Holmin T. Comparison between absorbable and nonabsorbable, monofilament sutures for end-to-end arterial anastomoses in growing pigs. Surgery. 1984 Feb;95(2):202–208. [PubMed]
  • Ray JA, Doddi N, Regula D, Williams JA, Melveger A. Polydioxanone (PDS), a novel monofilament synthetic absorbable suture. Surg Gynecol Obstet. 1981 Oct;153(4):497–507. [PubMed]
  • Laufer N, Merino M, Trietsch HG, DeCherney AH. Macroscopic and histologic tissue reaction to polydioxanone, a new, synthetic, monofilament microsuture. J Reprod Med. 1984 May;29(5):307–310. [PubMed]
  • Delbeke LO, Gomel V, McComb PF, Jetha N. Histologic reaction to four synthetic microsutures in the rabbit. Fertil Steril. 1983 Aug;40(2):248–252. [PubMed]
  • Houdart R, Lavergne A, Valleur P, Hautefeuille P. Polydioxanone in digestive surgery. An experimental study. Am J Surg. 1986 Sep;152(3):268–271. [PubMed]
  • Bourne RB, Bitar H, Andreae PR, Martin LM, Finlay JB, Marquis F. In-vivo comparison of four absorbable sutures: Vicryl, Dexon Plus, Maxon and PDS. Can J Surg. 1988 Jan;31(1):43–45. [PubMed]
  • Craig PH, Williams JA, Davis KW, Magoun AD, Levy AJ, Bogdansky S, Jones JP., Jr A biologic comparison of polyglactin 910 and polyglycolic acid synthetic absorbable sutures. Surg Gynecol Obstet. 1975 Jul;141(1):1–10. [PubMed]
  • JOHNSON J, KIRBY CK, ALLAM MW, HAGAN W. The growth of vascular anastomoses with continuous posterior and interrupted anterior silk sutures. Surgery. 1951 May;29(5):721–725. [PubMed]
  • Stillman RM, Sophie Z. Repair of growing vessels. Continuous absorbable or interrupted nonabsorbable suture? Arch Surg. 1985 Nov;120(11):1281–1283. [PubMed]
  • Chiu IS, Hung CR, Chao SF, Huang SH, How SW. Growth of the aortic anastomosis in pigs. Comparison of continuous absorbable suture with nonabsorbable suture. J Thorac Cardiovasc Surg. 1988 Jan;95(1):112–118. [PubMed]
  • Jatene AD, Fontes VF, Paulista PP, Souza LC, Neger F, Galantier M, Sousa JE. Anatomic correction of transposition of the great vessels. J Thorac Cardiovasc Surg. 1976 Sep;72(3):364–370. [PubMed]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute