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Arthritis Res. 2002; 4(Suppl 2): S11–S15.
Published online 2002 April 8. doi:  10.1186/ar547
PMCID: PMC3238215
The determination and measurement of functional disability in rheumatoid arthritis
Frederick Wolfecorresponding author1
1National Data Bank for Rheumatic Diseases-Arthritis Research Center Foundation and University of Kansas School of Medicine, Wichita, Kansas, USA
corresponding authorCorresponding author.
Frederick Wolfe: fwolfe/at/arthritis-research.org
Supplement
Current perspectives on the treatment of rheumatic diseases with infliximab
Peter E Lipsky and Ravinder N Maini
Supported by an educational grant from Centocor, Inc.
Received December 10, 2001; Revisions requested December 18, 2001; Revised February 13, 2002; Accepted February 15, 2002.
Abstract
Although functional outcome is frequently discussed and written about, it is often not clear what functional outcome is and how it can be measured. This paper introduces the concept of latent and observed measures of functional disability, and distinguishes between disability as a process measure and disability as an outcome measure. Using the Health Assessment Questionnaire as the main functional outcome measure in rheumatoid arthritis, we propose and discuss several methods for determining disability, and describe the implications of altering the disability course.
Keywords: disability, functional disability, Health Assessment Questionnaire, outcome, rheumatoid arthritis
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