Concerns about the “endangered physician-scientist” are not new.
1–3 Physicians have always found it challenging to juggle the demands of clinical care with the time required to learn research skills and perform investigations. Many physicians have also found it challenging to obtain the protected time that they need to start and maintain a research program,
4 to deal with the long time lag between beginning a research career and receiving R01 or similar funding,
5 and to cope with the career uncertainties related to the reliance on federal and other grants for salary support.
5 For these reasons, many have not been attracted to a career that combines clinical work with research. However, with today’s growing focus on the translation of basic science discoveries into clinical practice and the increased need for comparative effectiveness research, the demand for physician-scientists is likely to grow, as is the demand for new ideas and programs to increase the supply of physician-scientists.
In response to the many difficulties that physicians face when they attempt to pursue a research career, the National Institutes of Health (NIH) has established several supportive programs, including the NIH loan repayment program, career development awards, and the Clinical and Translational Science Award.
2 Similarly, universities have established various types of career development programs. While these programs are useful to young investigators,
6–8 they do not appear sufficient to substantially increase the cadre of well-trained physician-scientists, nor are they always successful in addressing the problems faced by specific groups of physicians who might be interested in pursuing investigative careers.
Studies indicate that women physicians, for example, are hindered by perceived gender bias,
9 a lack of role models in research,
10,11 difficulty finding mentors of the same sex,
11,12 perceived lack of institutional support,
13 and the challenges of raising a family while managing a research program.
13,14 For this population, issues related to work-life balance are particularly onerous and include problems related to scheduling meetings that do not conflict with previously planned child care responsibilities,
15 a lack of on-site or emergency child care,
13 a lack of lactation sites,
16 and a lack of promotion paths for part-time work.
13,17Like women, members of underrepresented minority groups report a dearth of role models in research.
3,18 Minorities also report discrimination at an institutional level
19,20 and insufficient efforts related to retention and promotion.
6,17,21 In addition, minorities describe difficulties in dealing with feelings of isolation,
19 financial burdens,
22 challenges associated with trying to balance a research career with the constant demand for their service on minority committees and their service as mentors for others in minority groups,
3 and lower levels of career satisfaction.
20To date, most studies of career development programs have tended to evaluate outcomes related to one or more specific program components. Various studies, for example, have demonstrated that mentoring has a positive impact on the career trajectories of physician-scientists, including those who are women and members of minority groups.
23–27 These studies have indicated that effective mentoring is associated with high research productivity,
28 increased professional socialization and interactions,
27 and greater satisfaction with salaries and promotions.
29,30 Moreover, a meta-analysis of results of mentoring studies has indicated that effective mentoring is associated with higher job satisfaction, greater self-esteem, greater organizational commitment, greater perception of promotion opportunities, lower work stress, and lower levels of work-family conflict.
31At the University of Pittsburgh’s Institute for Clinical Research Education (ICRE), which offers diverse training and career development programs in clinical and translational science for investigators throughout the pipeline, the career development programs include a mentoring component and numerous other successful training elements. However, we were interested in creating a comprehensive model for career success that would address multiple personal factors (e.g., demographics, education, and the psychosocial milieu) and organizational factors (e.g., financial resources, infrastructure, training, and mentoring) and would also take into account the complex and multifactorial interactions that occur between these personal and organizational factors. In addition, we were interested in creating a model that we could evaluate both in terms of the impact of its individual components and in terms of its overall impact on career success. Here, we describe the steps involved in developing and implementing such a model and establishing methods to evaluate its outcomes.