1. Beckham JC, Moore SD, Feldman ME, Hertzberg MA, Kirby AC, Fairbank JA. Health status, somatization, and severity of posttraumatic stress disorder in Vietnam combat veterans with posttraumatic stress disorder. Am J Psychiatry. 1998;155:1565–1569. [PubMed] 2. Boscarino JA. Diseases among men 20 years after exposure to severe stress: Implications for clinical research and medical care. Psychosom Med. 1997;59:605–614. [PubMed] 3. Qureshi SU, Pyne JM, Magruder KM, Schulz PE, Kunik ME. The link between post-traumatic stress disorder and physical comorbidities: a systematic review. Psychiatr Q. 2009;80:87–97. [PubMed] 4. Beckham JC, Calhoun PS, Glenn DM, Barefoot JC. Posttraumatic stress disorder, hostility, and health in women: A review of current research. Ann Behav Med. 2002;24(3):219–228. [PubMed] 5. Boscarino JA. Posttraumatic stress disorder and physical illness: Results from clinical and epidemiologic studies. Ann N Y Acad Sci. 2004;1032:141–153. [PubMed]
6. Beckham JC, Moore SD, Reynolds V. Interpersonal hostility and violence in Vietnam combat veterans with chronic posttraumatic stress disorder: A review of theoretical models and empirical evidence. Aggression and Violent Behavior. 2000;5:451–466.
7. Friedman MJ, Schnurr PP. The relationship between trauma, PTSD, and physical health. In: Friedman MJ, Charney DS, Deutch AY, editors. Neurobiological and clinical consequences of stress: From normal adaptation to PTSD. New York, NY: Lippincott-Raven; 1995. pp. 507–524.
8. Schnurr PP, Jankowski MK. Physical health and post-traumatic stress disorder: Review and synthesis. Semin Clin Neuropsychiatry. 1999;4:295–304. [PubMed] 9. Sibai AM, Fletcher AF, Armenian HK. Variations in the impact of long-term wartime stressors on mortality among the middle-aged and older population in Beirut, Lebanon, 1983–1993. Am J Epidemiol. 2001;154:128–137. [PubMed] 10. Kang HK, Bullman TA, Taylor JW. Risk of selected cardiovascular diseases and posttraumatic stress disorder among former World War II prisoners of war. Ann Epidemiol. 2006;16(5):381–386. [PubMed] 11. Lauterbach D, Vora R, Rakow M. The relationship between posttraumatic stress disorder and self-reported health problems. Psychosom Med. 2005;67(6):939–947. [PubMed] 12. Boscarino JA, Chang J. Electrocardiogram abnormalities among men with stress-related psychiatric disorders: Implications for heart disease and clinical research. Ann Behav Med. 1999;21:227–234. [PubMed] 13. Seng JS, Clark MK, McCarthy AM, Ronis DL. PTSD and physical comorbidity among women receiving Medicaid: Results from service-use data. J Trauma Stress. 2006;19:45–56. [PubMed] 14. Kubzansky LD, Koenen KC, Spiro A, Vokonas PS, Sparrow D. Prospective study of posttraumatic stress disorder symptoms and coronary heart disease in the Normative Aging Study. Arch Gen Psychiatry. 2007;64:109–116. [PubMed] 15. Boscarino JA. Posttraumatic stress disorder and mortality among U.S. Army veterans 30 years after military service. Ann Epidemiol. 2006;16:248–256. [PubMed] 16. O’Toole BI, Catts SV. Trauma, PTSD, and physical health: An epidemiological study of Australian Vietnam veterans. J Psychosom Res. 2008;64:33–40. [PubMed] 17. Dirkzwager AJE, Van der Velden PG, Grievink L, Yzermans CJ. Disaster-related posttraumatic stress disorder and physical health. Psychosom Med. 2007;69:435–440. [PubMed] 18. Kibler JL, Joshi K, Ma M. Hypertension in relation to posttraumatic stress disorder and depression in the US national comorbidity survey. Behav Med. 2009;34:125–131. [PubMed] 19. Santić Z, Lukić A, Sesar D, Milicević S, Ilakovac V. Long-term follow-up of blood pressure in family members of soldiers killed during the war in Bosnia and Herzegovina. Croatian Medical Journal. 2006;47(3):416–423. [PMC free article] [PubMed] 20. McFarlane AC, Atchison M, Rafalowicz E, Papay P. Physical symptoms in post-traumatic stress disorder. J Psychosom Res. 1994;38:715–726. [PubMed] 21. Sawchuk CN, Roy-Byrne P, Goldberg J, et al. The relationship between posttraumatic stress disorder, depression, and cardiovascular disease in an American Indian tribe. Psychol Med. 2005;35:1785–1794. [PubMed] 22. Kubzansky LD, Koenen KC, Jones AM, Eaton CA. A prospective study of posttraumatic stress disorder symptoms and coronary heart disease in women. Health Psychol. 2009;28(1):125–130. [PMC free article] [PubMed] 23. Boscarino JA. Psychobiologic predictors of disease mortality after psychological trauma: Implications for research and clinical surveillance. J Nerv Ment Dis. 2008;196:100–107. [PubMed] 24. Boscarino JA. A prospective study of PTSD and early-age heart disease mortality among Vietnam veterans: Implications for surveillance and prevention. Psychosom Med. 2008;70:668–676. [PMC free article] [PubMed] 25. Weisberg RB, Bruce SEMJT, Kessler R, Culpepper L, Keller MB. Nonpsychiatric illness among primary care patients with trauma histories and posttraumatic stress disorder. Psychiatr Serv. 2002;53(7):848–854. [PubMed] 26. Flood AM, Boyle SH, Calhoun PS, et al. Prospective study of externalizing and internalizing subtypes of posttraumatic stess disorder and their relationship to mortality in Vietnam veterans. Compr Psychiat. in press. [PMC free article] [PubMed] 27. Norman SB, Means-Christenson AJ, Craske MG, Sherbourne CD, Roy-Byrne P, Stein MB. Associations between psychological trauma and physical illness in primary care. J Trauma Stress. 2006;19:461–470. [PubMed] 28. Seng JS, Graham-Bermann SA, Clark MK, McCarthy AM, Ronis DL. Posttraumatic stress disorder and physical comorbidity among female children and adolescents: Results from service-use data. Pediatrics. 2005;116(6):e767–e776. [PubMed] 29. Goodwin RD, Davidson JR. Self-reported diabetes and posttraumatic stress disorder among adults in the community. Prev Med. 2005;40:570–574. [PubMed] 30. Sareen J, Cox BJ, Stein MB, Afifi TO, Fleet C, Asmundson GJ. Physical and mental comorbidity, disability, and suicidal behavior associated with posttraumatic stress disorder in a large community sample. Psychosom Med. 2007;69(3):242–248. [PubMed] 31. Blechert J, Michael T, Grossman P, Lajtman M, Wilhelm FH. Autonomic and respiratory characteristics of posttraumatic stress disorder and panic disorder. Psychosom Med. 2007;69(9):935–943. [PubMed] 32. Shalev A, Bleich A, Ursano RJ. Posttraumatic stress disorder: Somatic comorbidity and effort tolerance. Psychosom. 1990;31:197–203. [PubMed] 33. Buckley TC, Kaloupek DG. A meta-analytic examination of basal cardiovascular activity in posttraumatic stress disorder. Psychosom Med. 2001;63:585–594. [PubMed] 34. Newton TL, Parker BC, Ho IK. Ambulatory cardiovascular functioning in healthy postmenopausal women with victimization histories. Biol Psychol. 2005;70(2):121–130. [PubMed] 35. Jones-Alexander J, Blanchard EB, Hickling EJ. Psychophysiological assessment of youthful motor vehicle accident survivors. Applied Psychophysiology and Biofeedback. 2005;30(2):115–123. [PubMed] 36. Rabe S, Zöllner T, Maercker A, Karl A. Cardiovascular correlates of motor vehicle accident related posttraumatic stress disorder and its successful treatment. Applied Psychophysiology and Biofeedback. 2006;31(4):315–330. [PMC free article] [PubMed]
37. Hinton D, So V, Pollack MH, Pitman RK, Orr SP. The psychophysiology of orthostatic panic in Cambodian refugees attending a psychiatric clinic. J Psychopathol Behav Assess. 2004;26(1):1–13.
38. Pole N. The psychophysiology of posttraumatic stress disorder: A meta-analysis. Psychol Bull. 2007;133(5):725–746. [PubMed] 39. Orr SP, Metzger LJ, Pitman RK. Psychophysiology of post-traumatic stress disorder. Psychiatr Clin North Am. 2002;25(2):271–293. [PubMed] 40. Greenland P, Daviglus ML, Dyer AR, et al. Resting heart rate is a risk factor for cardiovascular and noncardiovascular mortality: The Chicago Heart Association Detection Project in Industry. Am J Epidemiol. 1999;149(9):853–862. [PubMed] 41. Veazey CH, Blanchard EB, Hickling EJ, Buckley TC. Physiological responsiveness of motor vehicle accident survivors with chronic posttraumatic stress disorder. Applied Psychophysiology and Biofeedback. 2004;29(1):51–62. [PubMed] 42. Obilom RE, Thacher TD. Posttraumatic stress disorder following ethnoreligious conflict in Jos, Nigeria. J Interpers Violence. 2008;23(8):1108–1119. [PubMed] 43. Lindauer RJ, Booij J, Habraken JB, et al. Effects of psychotherapy on regional cerebral blood flow during trauma imagery in patients with post-traumatic stress disorder: A randomized clinical trial. Psychol Med. 2007;38(4):543–554. [PubMed] 44. Buckley TC, Holohan D, Greif JL, Bedard M, Suvak M. Twenty-four-hour ambulatory assessment of heart rate and blood pressure in chronic PTSD and non-PTSD veterans. J Trauma Stress. 2004;17:163–171. [PubMed] 45. Forneris CA, Butterfield MI, Bosworth HB. Physiological arousal among women veterans with and without posttraumatic stress disorder. Mil Med. 2004;4:307–312. [PubMed] 46. Muraoka MY, Carlson JG, Chemtob CM. Twenty-four-hour ambulatory blood pressure and heart rate monitoring in combat-related posttraumatic stress disorder. J Trauma Stress. 1998;3:473–484. [PubMed] 47. Beckham JC, Feldman ME, Barefoot JC, et al. Ambulatory cardiovascular activity in Vietnam combat veterans with and without posttraumatic stress disorder. J Consult Clin Psychol. 2000;68:269–276. [PubMed] 48. Beckham JC, Taft CT, Vrana SR, et al. Ambulatory monitoring and physical health report in Vietnam veterans with and without chronic posttraumatic stress disorder. J Trauma Stress. 2003;16:329–335. [PubMed] 49. Orr SP, Metzger LJ, Lasko NB, et al. Physiologic responses to sudden loud tones in monozygotic twins discordant for combat exposure: Association with posttraumatic stress disorder. Arch Gen Psychiatry. 2003;60:283–288. [PubMed] 50. Griffin MG. A prospective assessment of auditory startle alterations in rape and physical assult survivors. J Trauma Stress. 2008;21(1):91–99. [PubMed] 51. Elsesser K, Sartory G, Tackenberg A. Attention, heart rate, and startle response during exposure to trauma-relevant pictures: a comparison of recent trauma victims and patients with posttraumatic stress disorder. J Abnorm Psychol. 2004;113(2):289–301. [PubMed] 52. Bremner JD, Vythilingam M, Vermetten E, et al. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology. 2003;28:733–750. [PubMed] 53. Casada JH, Roache JD. Dissociation of physiology and behavior in PTSD. Int J Psychophysiol. 2006;62(2):243–248. [PubMed] 54. Cuthbert BN, Lang PJ, Strauss C, Drobes D, Patrick CJ, Bradley MM. The psychophysiology of anxiety disorder: fear memory imagery. Psychophysiology. 2003;40(3):407–422. [PubMed] 55. Peckerman A, Dahl K, Chemitiganti R, LaManca JJ, Ottenweller JE, Natelson BH. Effects of posttraumatic stress disorder on cardiovascular stress responses in Gulf War veterans with fatiguing illness. Auton Neurosci. 2003;108(1–2):63–72. [PubMed] 56. Kibler JL, Lyons JA. Perceived coping ability mediates the relationship between PTSD severity and heart rate recover in veterans. J Trauma Stress. 2004;17(1):23–29. [PubMed] 57. Carson MA, Metzger LJ, Lasko NB, et al. Physiologic reactivity to startling tones in female Vietnam nurse veterans with PTSD. J Trauma Stress. 2007;20(5):657–666. [PubMed] 58. Wessa M, Flor H. Failure of extinction of fear responses in posttraumatic stress disorder: Evidence from second-order conditioning. Am J Psychiatry. 2007;164:1684–1692. [PubMed] 59. Ginsberg JP, Ayers E, Burriss L, Powell DA. Disruption of bradycardia associated with discriminative conditioning in combat veterans with PTSD. Neuropsychiatric Disease and Treatment. 2008;4(3):635–646. [PMC free article] [PubMed] 60. Muhtz C, Wester M, Yassouridis A, Widemann K, Kellner M. A combined dexamethasone/corticotropin-releasing hormone test in patients with chronic PTSD - first preliminary results. J Psychiatr Res. 2008;42:689–693. [PubMed] 61. Geracioti TD, Jr, Baker DG, Kasckow JW, et al. Effects of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorder. Psychoneuroendocrinology. 2008;33(4):416–424. [PubMed] 62. Strawn JR, Ekhator NN, Horn PS, Baker DG, Geracioti TD., Jr Blood pressure and cerebrospinal fluid norepinephrine in combat-related posttraumatic stress disorder. Psychosom Med. 2004;66:757–759. [PubMed] 63. Schmahl CG, Elzinga BM, Ebner UW, et al. Psychophysiological reactivity to traumatic and abandonment scripts in borderline personality and posttraumatic stress disorders: a preliminary report. Psychiatr Res. 2004;126:33–42. [PubMed] 64. Kellner M, Yassouridix A, Hubner R, Baker DG, Wiedermann K. Endocrine and cardiovascular responses to corticotropin-releasing hormone in patients with posttraumatic stress disorder: A role for atrial natriuretic peptide? Neuropsychobiology. 2003;47:102–108. [PubMed] 65. Schnurr PP, Spiro A, Paris AH. Physician-diagnosed medical disorders in relation to PTSD symptoms in older male military veterans. Health Psychol. 2000;19:91–97. [PubMed] 66. Luscher TF. 1993 Mack Forster Award Lecture: The endothelium as a target and mediator of cardiovascular disease. Eur J Clin Invest. 1993;23:670–685. [PubMed] 67. Harrison DG. Endothelial dysfunction in atherosclerosis. Basic Res Cardiol. 1994;89:87–102. [PubMed] 68. Celermajer DS, Sorenson KE, Gooch VM, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992;340:1111–1115. [PubMed] 69. Celermajer DS, Sorenson KE, Bull C, Robinson JH, Deanfield JE. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J Am Coll Cardiol. 1994;24:1468–1474. [PubMed]
70. Violanti JM, Andrew M, Burchfiel CM, Hartley TA, Charles LE, Miller DB. Post-traumatic stress symptoms and cortisol patterns among police officers. Policing: An International Journal of Police Strategies & Management. 2007;30(2):189–202.
71. Von Kanel R, Hepp U, Traber R, et al. Measures of endothelial dysfunction in plasma of patients with posttraumatic stress disorder. Psychiatr Res. 2008;158:363–373. [PubMed] 72. Von Kanel R, Hepp U, Buddeberg C, et al. Altered blood coagulation in patients with posttraumatic stress disorder. Psychosom Med. 2006;68:598–604. [PubMed] 73. Sloan RP, Shapiro PA, Bagiella E, Myers MM, Gormon JM. Cardiac autonomic control buffers blood pressure variability responses to challenge: A psychophysiologic model of coronary artery disease. Psychosom Med. 1999;61:58–68. [PubMed] 74. Sloan RP, Demeersman RE, Shapiro PA, et al. Cardiac autonomic control is inversely related to blood pressure variability responses to psychological challenge. Am J Physiol. 1997;272:H2227–H2232. [PubMed] 75. Cohen H, Kotler M, Matar MA, Kaplan Z, Miodownik H, Cassuto Y. Power spectral analysis of HR variability in posttraumatic stress disorder patients. Biol Psychiatry. 1997;4:627–629. [PubMed] 76. Hughes JW, Dennis MF, Beckham JC. Baroreceptor sensitivity at rest and during stress in women with posttraumatic stress disorder or major depressive disorder. J Trauma Stress. 2007;20(5):667–676. [PubMed] 77. Hughes JW, Feldman ME, Beckham JC. Posttraumatic stress disorder is associated with attenuated baroreceptor sensitivity among female, but not male, smokers. Biol Psychol. 2006;71:296–302. [PubMed] 78. Scheeringa MS, Zeanah CH, Myers L, Putnam F. Heart period and variability findings in preschool children with posttraumatic stress symptoms. Biol Psychiatry. 2004;55:685–691. [PubMed] 79. Ulmer CS, Calhoun PS, Edinger JD, Wagner HR, Beckham JC. Sleep disturbance and barorecptor sensitivity in women with posttraumatic stress disorder. J Traum Stress. 2009;22:643–647. [PMC free article] [PubMed] 80. Rich MW, Saini JS, Kleiger RE, Carney RM, TeVelde A, Freedland KE. Correlation of heart rate variability with clinical and angiography variables and late mortality after coronary angiography. Am J Cardiol. 1988;62:714–717. [PubMed] 81. Kleiger RE, Miller JP, Bigger JT, Moss AJ. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol. 1987;59:256–262. [PubMed] 82. Bilchick KC, Fetics B, Djoukeng R, et al. Prognostic value of heart rate variability in chronic congestive heart failure (Veterans Affairs’ Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure) Am J Cardiol. 2002;90:24–28. [PubMed] 83. Hopper JW, Spinazzola J, Simpson WB, Van der Kolk B. Preliminary evidence of parasympathetic influence on basal heart rate in posttraumatic stress disorder. J Psychosom Res. 2006;60:83–90. [PubMed] 84. Bigger JT, Fleiss JL, Rolnitzky LM, Steinman RC. The ability of several short-term measures of RR variability to predict mortality after myocardial infarction. Circulation. 1993;88:927–934. [PubMed] 85. Brosschot JF, Van Dijk E, Thayer JF. Daily worry is related to low heart rate variability during waking and the subsequent nocturnal sleep period. Int J Psychophysiol. 2007;63:39–47. [PubMed] 86. Hayano J, Jiang Y, Waugh R, O’Connor C, Frid D, Blumenthal JA. Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease. Am Heart J. 1997;134:411–418. [PubMed] 87. Bonnet MH, Arand DL. EEG arousal norms by age. J Clin Sleep Med. 2007;3:271–274. [PubMed] 88. Haley RW, Vongpatanasin W, Wolfe GI, et al. Blunted circadian variation in autonomic regulations of sinus node function in veterans with Gulf War syndrome. Am J Med. 2004;117:469–478. [PubMed] 89. Sack M, Hopper JW, Lamprecht F. Low respiratory sinus arrhythmia and prolonged psychophysiological arousal in posttraumatic stress disorder: Heart rate dynamics and individual differences in arousal regulation. Biol Psychiatry. 2004;55(3):284–290. [PubMed] 90. Bedi US, Arora R. Cardiovascular manifestations of posttraumatic stress disorder. Journal of the National Medical Association. 2007;99(6):642–649. [PMC free article] [PubMed] 91. Masi CB, Hawkley LC, Rickett EM, Cacioppo JT. Respiratory sinus arrhythmia and diseases of aging: Obesity, diabetes mellitus, and hypertension. Biol Psychol. 2007;74:212–223. [PMC free article] [PubMed] 92. Lehtinen J, Uusitupa M, Siitonen O, Pyorala K. Prevalence of neuropathy in newly diagnosed NIDDM and non diabetic control subjects. Diabetes. 1989;38:1307–1313. [PubMed] 93. Pfeifer MA, Weinberg CR, Cook D, et al. Autonomic neural dysfunction in recently diagnosed diabetic subjects. Diabetes Care. 1984;7:447–453. [PubMed] 94. Toyry JP, Niskanen LK, Mantysaari MJ, Lansimies EA, Uusitupa M. Occurrence predictors and clinical significance of autonomic neuropathy in NIDDM: Ten-year follow-up from the diagnosis. Diabetes. 1996;45:308–315. [PubMed] 95. Verrotti A, Chiarelli F, Morgese G. Autonomic dysfunction in newly diagnosed insulin-dependent diabetes mellitus children. Pediatr Neurol. 1996;14:49–52. [PubMed] 96. Watkins LL, Blumenthal JA, Davidson JRT, Babyak MA, McCants CB, Jr, Sketch MH., Jr Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease. Psychosom Med. 2006;68:651–656. [PubMed] 97. Kudat H, Akkaya B, Sozen AB, et al. Heart rate variability in diabetes patients. J Int Med Res. 2006;34:291–296. [PubMed] 98. Solter V, Thaller V, Karlovic D, Crnkovic D. Elevated serum lipids in veterans with combat-related chronic posttraumatic stress disorder. Croatian Medical Journal. 2002;43(6):685–689. [PubMed] 99. Trief PM, Ouimette P, Wade M, Shanahan P, Weinstock RS. Post-traumatic stress disorder and diabetes: Co-morbidity and outcomes in a male veterans sample. J Behav Med. 2006;29:411–418. [PubMed] 100. Karlovic D, Buljan D, Martinac M, Marcinko D. Serum lipid concentrations in Croatian veterans with posttraumatic stress disorder, posttraumatic stress disorder comorbid with major depressive disorder, or major depressive disorder. Journal of Korean Medical Sciences. 2004;19:431–436. [PMC free article] [PubMed] 101. Karlovic D, Martinac M, Buljan D, Zoricic Z. Relationship between serum lipid concentrations and posttraumatic stress disorder symptoms in soldiers with combat experiences. Acta Medica Okayama. 2004;58(1):23–27. [PubMed] 102. Maia DB, Marmar C, Mendlowicz MV, et al. Abnormal serum lipid profile in Brazilian police officers with post-traumatic stress disorder. J Affect Disord. 2008;107(1–3):259–263. [PubMed]
103. Friedman MJ, McEwen BS. Posttraumatic stress disorder, allostatic load, and medical illness. In: Schnurr PP, Green BL, editors. Trauma and Health: Physical Health Consequences of Exposure to Extreme Stress. Washington, DC: American Psychological Association; 2004. pp. 507–524.
104. McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med. 1998;338(3):171–179. [PubMed] 105. Reagan LP, Grillo CA, Piroli GG. The As and Ds of stress: Metabolic, morphological and behavioral consequences. Eur J Pharmacol. 2008;585:64–75. [PMC free article] [PubMed] 106. Chrousos GP, Gold PW. Editorial: A healthy body in a healthy mind - and vice versa - the damaging power of ‘uncontrollable stress’ Journal of Clinical Endocrinology. 1998;56:1842–1845. [PubMed] 107. Evans S, Giosan C, Patt I, Spielman l, Difede J. Anger and its association to distress and social/occupational functioning in symptomatic disaster relief works responding to the September 11, 2001, World Trade Center disaster. J Trauma Stress. 2006;19:147–152. [PubMed] 108. Orth U, Wieland E. Anger, hostility and posttraumatic stress disorder in trauma-exposed adults: A meta-analysis. J Consult Clin Psychol. 2006;74:698–706. [PubMed] 109. Jakupcak M, Conybeare D, Phelps L, et al. Anger, hostility, and aggression among Iraq and Afghanistan War veterans reporting PTSD and subthreshold PTSD. J Trauma Stress. 2007;20(6):945–954. [PubMed] 110. Begic D, Jokic-Begic N. Heterogeneity of posttraumatic stress disorder symptoms in Croatian war veterans: Retrospective study. Croatian Medical Journal. 2007;48(2):133–139. [PMC free article] [PubMed]
111. Cahill SP, Rauch SA, Hembree EA, Foa EB. Effect of cognitive-behavioral treatment for PTSD on anger. Journal of Cognitive Psychotherapy: An International Quarterly. 2003;17:113–131.
112. Taylor E. Outcome predictors for three PTSD treatments: Exposure, EMDR, and relaxation training. Journal of Cognitive Psychotherapy: An International Quarterly. 2003;17:149–162.
113. van Minnen A, Arntz A, Keijsers GP. Prolonged exposure in patients with chronic PTSD: Predictors of treatment outcome and dropout. Behav Res Ther Apr. 2002;40(4):439–457. [PubMed] 114. Stapleton JA, Taylor S, Asmundson GJG. Effects of three PTSD treatments on anger and guilt: Exposure therapy, eye movement desensitization and reprocessing, and relaxation training. J Trauma Stress. 2006;19:19–28. [PubMed] 115. Beckham JC, Vrana SR, Barefoot JC, Feldman ME, Fairbank JA, Moore SM. Magnitude and duration of cardiovascular responses to anger in Vietnam veterans with and without posttraumatic stress disorder. J Consult Clin Psychol. 2002;70:228–234. [PubMed] 116. Shapiro D, Goldstein IB, Jamner LD. Effects of clinical hostility, anger out, and defensiveness on ambulatory blood pressure in black and white college students. Psychosom Med. 1996;58:354–364. [PubMed] 117. Enkelman HCH, Bishop GD, Tong EMW, et al. The relationship of hostility, negative affect and ethnicity to cardiovascular responses: An ambulatory study in Singapore. Int J Psychophysiol. 2005;56(2):185–197. [PubMed] 118. Shapiro D, Jamner LD, Goldstein IB. Daily mood states and ambulatory blood pressure. Psychophysiology. 1997;34:399–405. [PubMed] 119. Adams SH, Cartwright LK, Ostrove JM, Stewart AJ, Wink P. Psychological predictors of good health in three longitudinal studies of educated midlife women. Health Psychol. 1998;17:412–420. [PubMed] 120. Calhoun PS, Bosworth HB, Siegler IC, Bastian LA. The relationship between hostility and behavioral risk factors for poor health in women veterans. Prev Med. 2001;33:552–557. [PubMed] 121. Miller TQ, Smith TW, Turner CW, Guijarro ML, Hallet AJ. A meta-analytic review of research on hostility and physical health. Psychol Bull. 1996;119:322–348. [PubMed] 122. Butterfield MI, Forneris CA, Feldman ME, Beckham JC. Hostility and functional health status in women veterans with posttraumatic stress disorder versus women with other primary psychiatric diagnosis: A preliminary study. J Trauma Stress. 2000;13:735–741. [PubMed]
123. Kilpatrick DB, Resick PA, Veronen LJ. Effects of a rape experience: A longitudinal study. Journal of Social Issues. 1981;37:1–17.
124. Kulka RA, Schlenger WE, Fairbank JA, et al. Trauma and the Vietnam War Generation: Report of Findings from the National Vietnam Veterans Readjustment Study. New York: Brunner/Mazel; 1990.
125. Zlotnick C, Zakriski AL, Shea MT, Costello E. The long-term sequelae of sexual abuse: Support for a complex posttraumatic stress disorder. J Trauma Stress. 1996;9:195–205. [PubMed] 126. Blake DD, Weathers FW, Nagy LM, et al. The development of a clinician-administered posttraumatic stress disorder scale. J Trauma Stress. 1995;8:75–80. [PubMed]
127. Barefoot JC, Lipkus IM. The assessment of anger and hostility. In: Siegman AW, Smith TW, editors. Anger, Hostility, and the Heart. Hillsdale, NJ: Lawrence Erlbaum; 1994. pp. 67–96.
128. Smith TW. Hostility and health: Current status of a psychosomatic hypothesis. Health Psychol. 1992;11:139–150. [PubMed] 129. Dujovne VF, Houston BK. Hostility-related variables and plasma lipid levels. J Behav Med. 1991;14:555–565. [PubMed] 130. Knox SS, Jacobs DR, Jr, Chesney MA, Raczynski J, McCreath H. Psychosocial factors and plasma lipid levels in black and white young adults: The Coronary Artery Risk in Young Adults Study data. Psychosom Med. 1996;58:365–373. [PubMed] 131. Lane JD, Pieper CF, Barefoot JC, Williams RB, Siegler I. Caffeine and cholesterol: Interactions with hostility. Psychosom Med. 1994;56:260–266. [PubMed] 132. Lundberg U, Hedman M, Melin B, Frankenhaeuser M. Type A behavior in healthy males and females as related to physiological reactivity and blood lipids. Psychosom Med. 1989;51:113–122. [PubMed] 133. Pope ML, Smith TW. Cortisol excretion in high and low cynically hostile men. Psychosom Med. 1991;53:386–392. [PubMed] 134. Siegler I, Peterson BL, Barefoot JC, Williams RB. Hostility during late adolescence predicts coronary risk factors at mid-life. Am J Epidemiol. 1992;136:146–154. [PubMed] 135. Suarez EC, Bates MP, Harralson TL. The relation of hostility to lipids and lipoproteins in women: Evidence for the role of antagonistic hostility. Ann Behav Med. 1998;20:59–63. [PubMed] 136. Vogele C. Serum lipid concentrations, hostility and cardiovascular reactions to mental stress. Int J Psychophysiol. 1998;28:167–179. [PubMed] 137. Weidner G, Boughal T, Connor SL, Pieper CF, Mendell NR. Relationship of job strain to standard coronary risk factors and psychological characteristics in women and men of the Family Heart Study. Health Psychol. 1997;16:239–247. [PubMed] 138. Nelson TL, Palmer RF, Pedersen NL. The metabolic syndrome mediates the relationship between cynical hostility and cardiovascular disease. Exp Aging Res. 2004;30:163–177. [PubMed] 139. Zhang J, Niaura R, Todaro JF, et al. Suppressed hostility predicted hypertension incidence among middle-aged men: The normative aging study. J Behav Med. 2005;28:443–454. [PubMed] 140. Zhang J, Niaura R, Dyer JR, et al. Hostility and urine norepinephrine interact to predict insulin resistance: The VA Normative Aging Study. Psychosom Med. 2006;68:718–726. [PubMed] 141. Anderson DE, Metter EJ, Hougaku H, Najjar SS. Suppressed anger is associated with increased carotid arterial stiffness in older adults. Am J Hypertens. 2006;19:1129–1134. [PubMed] 142. Krantz DS, Olson SB, Francis JL, et al. Anger, hostility, and cardiac symptoms in women with suspected coronary artery disease: The Women’s Ischemia Syndrome Evaluation (WISE) Study. J Womens Health. 2006;15:1214–1223. [PubMed] 143. Adams SH. Role of hostility in women’s health during mid-life: A longitudinal study. Health Psychol. 1994;13:488–495. [PubMed] 144. Barefoot JC, Larsen S, Lieth LVD, Schroll M. Hostility, incidence of acute myocardial infarction, and mortality in a sample of older Danish men and women. Am J Epidemiol. 1995;142:477–484. [PubMed] 145. Cartwright LK, Wink P, Kmetz C. What leads to good health in midlife women physicians? Some clues from a longitudinal study. Psychosom Med. 1995;57:284–292. [PubMed] 146. Knox SS, Siegmund KD, Weidner G, Ellison RC, Adelman A, Paton C. Hostility, social support, and coronary heart disease in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Cardiol. 1998;82:1192–1196. [PubMed] 147. Lahad A, Heckbert SR, Koepsell TD, Psaty BM, Patrick DL. Hostility, aggression, and the risk of nonfatal myocardial infarction in postmenopausal women. J Psychosom Res. 1997;43:183–195. [PubMed] 148. Matthews KA, Owens JF, Kuller LH, Sutton-Tyrrell K, Jansen-McWilliams L. Are hostility and anxiety associated with carotid atherosclerosis in healthy postmenopausal women? Psychosom Med. 1998;60:633–638. [PubMed] 149. Smith TW, Glazer K, Ruiz JM, Gallo LC. Hostility, anger, aggressiveness, and coronary heart disease: An interpersonal perspective on personality, emotion, and health. J Pers. 2004;76:1217–1270. [PubMed] 150. Raikkonen K, Matthews KA, Kuller LH, Reiber C, Bunker CH. Anger, hostility and visceral adipose tissue in healthy postmenopausal women. Metabolism. 1999;48:1146–1152. [PubMed] 151. Raikkonen K, Mathews KA, Kuller LH. Trajectory of psychological risk and incident hypertension in middle-aged women. Hypertension. 2001;38:798–802. [PubMed] 152. Raikkonen K, Mathews KA, Kuller LH. The relationship between psychological risk attributes and the metabolic syndrome in healthy women: Antecedent or consequence? Metabolism. 2002;51:1573–1577. [PubMed] 153. D’Antono B, Moskowitz DS, Miners C, Archambault J. Gender and communal trait differences in the relations among social behaviour, affect arousal, and cardiac autonomic control. J Behav Med. 2005;28(3):267–279. [PubMed]
154. Violanti JM, Andrew ME, Burchfiel CM, Dorn J, Hartley T, Miller DB. Posttraumatic stress symptoms and subclinical cardiovascular disease in police officers. International Journal of Stress Management. 2006;13(4):541–554.
155. Anderson CM, Linden W, Habra ME. The importance of examining blood pressure reactivity and recovery in anger provocation research. Int J Psychophysiol. 2005;57(3):159–163. [PubMed] 156. Broadwell SD, Light KC. Hostility, conflict and cardiovascular response in married couples: A focus on the dyad. Int J Behav Med. 2005;12(3):142–152. [PubMed] 157. Everson-Rose SA, Lewis TT. Psychosocial factors and cardiovascular diseases. Annual Review of Public Health. 2005;26(1):469–500. [PubMed] 158. Everson-Rose SA, Lewis TT, Karavolos K, Matthews KA, Sutton-Tyrrell K, Powell LH. Cynical hostility and carotid atherosclerosis in African American and white women: The Study of Women’s Health Across the Nation (SWAN) Heart Study. Am Heart J. 2006;152(5):982.e987–913. [PubMed] 159. Suarez EC. Sex differences in the relation of depressive symptoms, hostility, and anger expression to indices of glucose metabolism in nondiabetic adults. Health Psychol. 2006;25:484–492. [PubMed] 160. Gottdiener JS, Kop WJ, Hausner E, McCeney MK, Herrington D, Krantz DS. Effects of mental stress on flow-mediated brachial arterial dilation and influence of behavioral factors and hypercholesterolemia in subjects without cardiovascular disease. Am J Cardiol. 2003;92(6):687–691. [PubMed] 161. Ouimette P, Cronkite R, Henson BR, Prins A, Gima K, Moos RH. Posttraumatic stress disorder and health status among female and male medical patients. J Trauma Stress. 2004;17:1–9. [PubMed] 162. Beckham JC, Flood AM, Dennis MF, Calhoun PS. Ambulatory cardiovascular activity and hostility ratings in women with posttraumatic stress disorder. Biol Psychiatry. 2009;65:268–272. [PMC free article] [PubMed] 163. Ouimette P, Cronkite R, Prins A, Moos RH. Posttraumatic stress disorder, anger and hostility, and physical health status. J Nerv Ment Dis. 2004;192(8):563–566. [PubMed] 164. Benotsch EG, Christensen AJ, McKelvey L. Hostility, social support and ambulatory cardiovascular activity. J Behav Med. 1997;20:163–176. [PubMed] 165. Christensen AJ, Smith TW. Cynical hostility and cardiovascular reactivity during self-disclosure. Psychosom Med. 1993;55:193–202. [PubMed]
166. Houston BK. Anger, hostility, and psychophysiological reactivity. In: Siegman AW, Smith TW, editors. Anger, Hostility, and the Heart. Hillsdale, NJ: Lawrence Erlbaum; 1994. pp. 97–115.
167. Suarez EC, Kuhn CM, Schanberg SM, Williams RB, Zimmering EA. Neuroendocrine, cardiovascular, and emotional responses of hostile men: The role of interpersonal challenge. Psychosom Med. 1998;60:78–88. [PubMed]
168. Williams RB, Barefoot JC, Shekelle RB. The health consequences of hostility. In: Chesney MA, Rosenman RH, editors. Anger and Hostility in Cardiovascular and Behavioral Disorders. Washington, DC: Hemisphere; 1985. pp. 173–185.
169. Brosschot JF, Thayer JF. Anger inhibition, cardiovascular recovery, and vagal function: A model of the link between hostility and cardiovascular disease. Ann Behav Med. 1998;20:326–332. [PubMed] 170. Kaufman ML, Kimble MO, Kaloupek DG, et al. Peritraumatic dissociation and physiological response to trauma-relevant stimuli in Vietnam combat veterans with posttraumatic stress disorder. J Nerv Ment Dis. 2002;190(3):167–174. [PubMed] 171. Vidović A, Vilibić M, Markotić A, et al. Baseline level of platelet-leukocyte aggregates, platelet CD63 expression, and soluble P-selectin concentration in patients with posttraumatic stress disorder: A pilot study. Psychiatr Res. 2007;150(2):211–216. [PubMed]
172. Ford DE. Depression, trauma, and cardiovascular health. In: Schnurr PP, Green BL, editors. Trauma and Health: Physical Consequences of Exposure to Extreme Stress. Washington, DC: American Psychological Association; 2004. pp. 73–98.
173. Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity and comorbidity of 12-month DSM-IV Disorders in the National Comorbidity Survey replication. Arch Gen Psychiatry. 2005;62:617–627. [PMC free article] [PubMed] 174. Keane TM, Kaloupek DG. Comorbid psychiatric disorders in PTSD: Implications for research. Ann N Y Acad Sci. 1997;821:24–34. [PubMed] 175. Carney RM, Blumenthal JA, Freedland KE, et al. Low heart rate variability and the effect of depression on post-myocardial infarction mortality. Arch Intern Med. 2005;165:2024–2028. [PubMed] 176. Krittayaphong R, Cascio WE, Light KC, et al. Heart rate variability in patients with coronary artery disease: Differences in patients with higher and lower depression scores. Psychosom Med. 1997;59:231–235. [PubMed] 177. Sherwood A, Hinderliter AL, Watkins LL, Waugh RA, Blumenthal JA. Impaired endothelial function in coronary heart disease patients with depressive symptomatology. J Am Coll Cardiol. 2005;46:656–659. [PubMed] 178. Boyle SH, Surwit RS, Georgiades A, et al. Depressive symptoms, race, and glucose concentrations. Diabetes Care. 2007;30(10):2484–2488. [PubMed] 179. McCaffery JM, Niaura R, Todaro JF, Swan GE, Carmelli D. Depressive symptoms and metabolic risk in adult male twins enrolled in the National Heart, Lung, and Blood Institute Twin Study. Psychosom Med. 2003;65:490–497. [PubMed] 180. Carnethon MR, Kinder LS, Fair JM, Stafford RS, Fortmann SP. Symptoms of depression as a risk factor for incident diabetes: Findings from the National Health and Nutrition Examination Epidemiologic Follow-Up Study, 1971–1992. Am J Epidemiol. 2003;158:416–423. [PubMed] 181. Everson-Rose SA, Torrens JI, Meyer PM, et al. Depressive symptoms, insulin resistance and risk of diabetes in women at midlife. Diabetes Care. 2004;27:2856–2862. [PubMed] 182. Beckham JC. Smoking and anxiety in combat veterans with chronic posttraumatic stress disorder: A review. J Psychoactive Drugs. 1999;31(2):103–110. [PubMed]
183. Schnurr PP, Green BL, editors. Trauma and Health: Physical Health Consequences of Exposure to Extreme Stress. Washington, DC: American Psychological Association; 2004.
184. Fu S, McFall M, Saxon AJ, et al. Posttraumatic stress disorder and smoking: A systematic review. Nicotine Tob Res. 2007;9:1071–1084. [PubMed] 185. Beckham JC, Dennis MF, McClernon FJ, Mozley SL, Collie CF, Vrana SR. The effects of cigarette smoking on script-driven imagery in smokers with and without posttraumatic stress disorder. Addict Behav. 2007;32:2900–2915. [PMC free article] [PubMed] 186. Houston BK, Vavak CR. Hostility: Developmental factors, psychosocial correlates, and health behaviors. Health Psychol. 1991;10:9–17. [PubMed] 187. Scherwitz LW, Perkins LL, Chesney MA, Hughes GH, Sidney S, Manalio TA. Hostility and health behaviors in young adults: The CARDIA study. Am J Epidemiol. 1992;136:136–145. [PubMed] 188. Leiker M, Hailey BJ. A link between hostility and disease: Poor health habits? Behav Med. 1988;3:129–133. [PubMed] 189. Miller TQ, Markides KS, Chiriboga DA, Ray LA. A test of the psychosocial vulnerability and health behavior models of hostility: Results from an 11-year follow-up study of Mexican Americans. Psychosom Med. 1995;57:572–581. [PubMed] 190. Sidney S, Sternfeld B, Haskell WL, Jacobs DR, Jr, Chesney MA, Hulley SB. Television viewing and cardiovascular risk factors in young adults: The CARDIA study. Ann Epidemiol. 1996;6:154–159. [PubMed] 191. Whiteman MC, Fowkes FG, Deary IJ, Lee AJ. Hostility, cigarette smoking and alcohol consumption in the general population. Soc Sci Med. 1997;44:1089–1096. [PubMed] 192. Koskenvuo M, Kaprio J, Rose RJ, et al. Hostility as a risk factor for mortality and ischemic heart disease in men. Psychosom Med. 1988;50:330–340. [PubMed] 193. Shekelle RB, Gale M, Ostfeld AM, Paul O. Hostility, risk of coronary disease and mortality. Psychosom Med. 1983;45:109–114. [PubMed] 194. Ouimette P, Goodwin E, Brown PJ. Health and well being of substance use disorder patients with and without posttraumatic stress disorder. Addict Behav. 2006;31(8):1415–1423. [PubMed] 195. David D, Woodward C, Esquenazi J, Mellman TA. Comparison of comorbid physical illnesses among veterans with PTSD and veterans with alcohol dependence. Psychiatr Serv. 2004;55(1):82–85. [PubMed] 196. Pole N, Neylan TC, Otte C, Henn-Hasse C, Metzler TJ, Marmar CR. Prospective prediction of posttraumatic stress disorder symptoms using fear potentiated auditory startle responses. Biol Psychiatry. 2009;65:235–240. [PMC free article] [PubMed] 197. True WR, Rice J, Eisen SA, Heath AC. A twin study of genetic and environmental contributions to liability for posttraumatic stress symptoms. Arch Gen Psychiatry. 1993;50(4):257–265. [PubMed] 198. Koenen KC, Anstadter AB, Nugent NR. Gene-environment interaction in posttraumatic stress disorder: An update. J Trauma Stress. 2009;22(5):416–426. [PMC free article] [PubMed] 199. Pitman RK, Gilbertson MW, Gurvits TV, et al. Clarifying the origin of biological abnormalities in PTSD through the study of identical twins discordant for combat exposure. Ann N Y Acad Sci. 2006;1071:242–254. [PMC free article] [PubMed] 200. Breslau N, Kessler R, Chilcoat H, Schultz L, Davis G, Andreski P. Trauma and posttraumatic stress disorder in the community: The 1996 Detroit Area Survey of Trauma. Arch Gen Psychiatry. 1998;55(7):626–632. [PubMed] 201. Breslau N. Epidemiologic studies of trauma, posttraumatic stress disorder, and other psychiatric disorders. Can J Psychiatry. 2002;47(10):923–929. [PubMed] 202. Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey replication. Arch Gen Psychiatry. 2005;62:593–602. [PubMed] 203. Boscarino JA. External-cause mortality after psychologic trauma: The effects of stress exposure and predisposition. Compr Psychiatry. 2006;47:503–514. [PubMed] 204. Norquist GS, Regier DA. The epidemiology of psychiatric disorders and the de facto mental health care system. Annual Review of Medicine. 1996;47:473–479. [PubMed] 205. Elofsson UOE, von Schèele B, Theorell T, Söndergaard HP. Physiological correlates of eye movement desensitization and reprocessing. J Anxiety Disord. 2008;22(4):622–634. [PubMed] 206. Sack M, Lempa W, Steinmetz A, Lamprecht F, Hofmann A. Alterations in autonomic tone during trauma exposure using eye movement desensitization and reprocessing (EMDR)-Results of a preliminary investigation. J Anxiety Disord. 2008;22:1264–1271. [PubMed] 207. Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK. Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. Journal of Psychiatry Research. 2008;42:503–506. [PubMed] 208. Tucker P, Beebe KL, Burgin C, et al. Paroxetine treatment of depression with posttraumatic stress disorder: Effects on autonomic reactivity and cortisol secretion. J Clin Psychopharmacol. 2004;24(2):131–140. [PubMed]
209. Blanchard EB, Hickling EJ, Veazey CH, et al. Treatment-related changes in cardiovascular reactivity to trauma cues in motor vehicle accident-related PTSD. Behavior Therapy. 2002;33(3):417–426.
210. Finch SJ, van Zyl LT. Cardioversion of persistent atrial arrhythmia after treatment with venlafaxine in successful management of major depression and posttraumatic stress disorder. Psychosom. 2006;47(6):533–536. [PubMed] 211. Mitani S, Fujita M, Sakamoto S, Shirakawa T. Effect of autogenic training on cardiac autonomic nervous activity in high-risk fire service workers for posttraumatic stress disorder. J Psychosom Res. 2006;60:439–444. [PubMed] 212. Nishith P, Duntley SP, Domitrovich PP, Uhles ML, Cook BJ, Stein PK. Effect of cognitive behavioral therapy on heart rate variability during REM sleep in female rape victims with PTSD. J Trauma Stress. 2003;16(3):247–250. [PubMed]
213. Nishith P, Griffin MG. Utility of the heart rate response as an index of emotional processing in a female rape victim with posttraumatic stress disorder. Cognitive & Behavioral Practice. 2002;9:302–307.
214. Von Kanel R, Hepp U, Kraemer B, et al. Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res. 2007;41:744–752. [PubMed] 215. MacKinnon DP, Fairchild AJ, Fritz MS. Mediation analysis. Annu Rev Psychol. 2007;58:593–614. [PMC free article] [PubMed]