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Adv Pharmacol Sci. 2012; 2012: 789713.
Published online Nov 1, 2011. doi:  10.1155/2012/789713
PMCID: PMC3206388
Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook)
Vaishali D. Shewale, 1, 2 Tushar A. Deshmukh, 1, 2 * Liladhar S. Patil, 1, 3 and Vijay R. Patil 1, 2
1Tapi Valley Education Society, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, India
2Department of Pharmacognosy, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, Maharashtra, India
3Department of Biotechnology, Hon'ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, Maharashtra, India
*Tushar A. Deshmukh: deshmukhta/at/rediffmail.com
Academic Editor: Lutfun Nahar
Received August 24, 2011; Accepted September 8, 2011.
Abstract
The present work was to evaluate the anti-inflammatory activity of Delonix regia leaves (Family: Caesalpiniaceae). The powder of Delonix regia leaves was subjected to extraction with ethanol in soxhlet extractor. The ethanol extract after preliminary phytochemical investigation showed the presence of sterols, triterpenoids, phenolic compounds and flavonoids. The anti-inflammatory activity was studied using carrageenan-induced rat paw edema and cotton pellet granuloma at a three different doses (100, 200, and 400 mg/kg b.w. p.o.) of ethanol extract. The ethanol extract of Delonix regia leaves was exhibited significant anti-inflammatory activity at the dose of 400 mg/kg in both models when compared with control group. Indomethacin (10 mg/kg b.w. p.o) was also shown significant anti-inflammatory activity in both models.
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