A 16-old-boy was admitted in the Dharamshila Cancer Hospital and Research Centre, New Delhi, on February 05, 1997 with complaints of bone pains for the last 2 months and fever for last one month. His bone marrow aspiration study done earlier from Indraprastha Apollo Hospital on February 07, 1997 suggested acute lymphoblastic leukemia (ALL) L2. However, immunophenotyping study diagnosed it as AML – M0. The bone marrow pathology showed 85% blast. The patient was given two cycles of induction chemotherapy (3+7 protocol) with daunomycin and cytosine arabinoside cytosar , following which the patient achieved incomplete remission with bone marrow aspirate showing 14% blast. Subsequently, patient received two cycles of high-dose cytosine arabinoside Ara-C . The bone marrow study done on May 21, 1997 after the completion of first cycle showed less than 1% blast cells. The patient completed the second cycle of chemotherapy on June 01, 1997. During chemotherapy, the patient had 3 to 4 episodes of infection for which antibiotic coverage was given along with supportive care. However, bone marrow studies done on August 29, 1997 indicated relapse of the disease. Peripheral blood smear showed 6% blast cells and bone marrow showed 40% blast cells. The option of further chemotherapy and/or bone marrow transplant was discussed with the patient. However, the caregivers of the patient did not consent for any of the two options. The patient volunteered for the Ayurvedic therapy that started from September 09, 1997.
The patient was given oral AYT comprising of Navjeevan, Valapani, Kamdhuda
] etc . The patients was given supportive therapy for fever and infection time to time after getting culture and drug sensitivity test under the guidance of a competent MD, modern medicines. No other Ayurvedic
medicines were given. The details of the medicines are given in . These medicines were found to be effective in the treatment of leukemia patients.[6
] The patient was clinically asymptomatic at the time of the start of the AYT. The patient tolerated the therapy well and cytopathology studies done about 6 months after the start of AYT on March 09, 1998 showed about 1% blast cells in bone marrow, whereas no blast cell was found in peripheral blood. The patient continued the Ayurvedic
therapy with regular follow-up. Patient was followed up on monthly basis. Apart from clinical condition, his body weight and CBC were checked on monthly basis using the same pathology run by a MD, pathology at Dehradun or Dr lal Path lab in Delhi. The peripheral blood smear study done at regular interval did not show any abnormality. The AYT was continued for five years and stopped. Thereafter, the patient received intermittent maintenance AYT, same as mentioned before, in the same doses for three months in the next two years.
Details of the Ayurvedic medicines
In October 2007, the patient developed a testicular lesion suspected to be tuberculosis. However, cytology studies of the lesion, PCR analysis, and semen culture were all negative. The AYT was restarted for six months from November 2007. At present, the patient is normal and healthy and has completed 12 years of disease-free survival with AYT.