Patients
There were 95 patients in the hospital when data were gathered in February and March 2010, 8 women and 87 men. The mean age was 40.9 years (95% confidence interval 38.4 to 43.5). The mean length of stay was 7.2 years (95% confidence interval 5.3 to 9.2 years). The acute/high secure cluster included the women's unit, the men's admission unit and an intensively staffed men's unit, 25 (26%) patients in all. In some of the analyses that follow, only male patients are included because women are part of a separate recovery pathway. The medium cluster units comprised of two medium secure units for men and one slow-stream or longer term low secure unit, 40 (42%) patients in all. The pre-discharge and community service had 30 (32%) patients.
Primary diagnosis was schizophrenia in 68 (72%), schizoaffective disorder in 8 (8%), bi-polar affective disorder in 11 (12%), psychotic depression in 5 (5%) and intellectual disability in 3 (3%). There were 25 (26%) patients transferred from prisons, 8 (8%) detained because unfit to stand trial, 46 (48%) not guilty by reason of insanity and 16 (17%) who were detained under the civil mental health act and transferred from local psychiatric services.
No leave outside the hospital was permitted for 55 (58%) patients, 20 (21%) were allowed leave accompanied by staff and 20 (21%) were allowed unaccompanied leave as part of their pre-discharge rehabilitation programmes.
Inter-Rater Reliability
The ratings of 21 of the patients using the DUNDRUM-3 and DUNDRUM-4 by the researchers (SO'D and MD) were replicated over the period of data collection by HGK, who was blind to the ratings of SO'D and MD. The kappa statistic could be calculated for 7 of the 13 items and ranged between 0.44 and 0.77 (all p < 0.001). For all 13 items the X2 linear by linear association was greater than 6.9 (df = 1, p < 0.01) and the Spearman rank correlation coefficient was greater than 0.51 (range 0.51 to 0.95, all p < 0.02). For items rated 0 to 4, random agreement between two raters can be expected in 5 out of 25 'cells' i.e. 20% of cases. a probability of 0.2. For the DUNDRUM-3 programme completion items, there was exact agreement between the two raters for item 1 in 19 of 21 cases (90%, binomial exact probability p < 0.001), exact agreement for items 2 and 3 in 16/21 (76%, p < 0.001), for item 4 in 13/21 (62%, p < 0.001), for items 5 and 6 in 18/21 (86%, p < 0.001) and exact agreement for item 7 in 17/21 (81%, p < 0.001). For the DUNDRUM-4 recovery items there was exact agreement between the two raters for item 1 in 14/21 cases (67%, p < 0.001), for item 2 in 16/21 (76%, p < 0.001), for item 3 in 17/21 (81%, p < 0.001), for item 4 in 13/21 (62%, p < 0.001), for item 5 in 18/21 (86%, p < 0.001) and for item 6 in 15/21 (71%, p < 0.001).
Internal consistency
The seven programme completion items were subjected to a principle components factor analysis. All statistics are for 95 patients. Initial extraction yielded one factor with an Eigen value of 4.65 accounting for 66% of the variance and other factors had Eigen values less than 1. All seven items loaded positively on the first factor (r values all >0.724). Cronbach's alpha statistic for the seven Programme Completion items was 0.911. Cronbach's alpha if any one item was deleted was in the range 0.886 to 0.911.
The six recovery items were subjected to a principle components factor analysis. Initial extraction yielded one factor with an Eigen value of 3.9 accounting for 66% of the variance and other factors had Eigen values less than 1. All six items loaded positively on this first factor (r values all >0.75). Cronbach's alpha statistic for the six recovery items was 0.890. Cronbach's Alpha if any one item was omitted was in the range 0.845 to 0.885 except for item 6 'victim sensitivities' deletion of which led to an increase of the alpha statistic to 0.982, a negligible change.
Factor analysis on all thirteen items together yielded two components with Eigen values greater than 1. The first had an Eigen value of 7.7 and accounted for 59% of the variance while the second had an Eigen value of 1.3 and accounted for 9.8% of the variance. All thirteen items loaded strongly positively on the first component (all r > 0.575), while all the recovery items loaded positively on the second component with five of the seven programme completion items loading negatively on the second component. Only two programme completion items, programme completion item 4 'problem behaviours' and programme completion item 7 'family and social networks' loaded positively on the second component. Cronbach's Alpha for the combined scale of thirteen items was 0.94 and only one item if omitted lead to an increase in the Alpha statistic. This was recovery item 6 'victim sensitivity', omission of which gave an alpha of 0.941, a negligible increase. Because of the face validity of the two scales as distinct in content and because of the result of the factor analysis for all thirteen items, it appears reasonable to treat them as separate for validation purposes, while also accepting that they could be used as a single score for validation purposes. The DUNDRUM-3 Programme Completion and DUNDRUM-4 Recovery scores correlated with each other (Spearman r = +0.730, p < 0.001)
Possible confounders
Age correlated poorly with the DUNDRUM-3 Programme completion score (Spearman r = -0.205, p = 0.047) and did not correlate significantly with the DUNDRUM-4 Recovery score (r = -0.205, NS) or the total score for all 13 items (r = -0.175, NS).
Length of stay correlated inversely but weakly with the DUNDRUM-3 Programme completion score (r = -0.337, p < 0.001), with the DUNDRUM-4 Recovery score (r = -0.352, p < 0.001) and with the total for all 13 items (r = -0.348, p < 0.001).
Men and women did not differ significantly for mean scores in DUNDRUM-3 Programme completion, DUNDRUM-4 Recovery or combined scores.
The PANSS positive symptom score correlated 0.516 with the DUNDRUM-3 programme completion score and 0.656 with the DUNDRUM-4 Recovery score. The PANSS negative symptom score correlated 0.525 with the DUNDRUM-3 programme completion score and 0.487 with the DUNDRUM-4 recovery score. The PANSS general symptom score correlated 0.506 with the DUNDRUM-3 programme completion score and 0.495 with the DUNDRUM-4 recovery score. The PANSS total score correlated 0.574 with the DUNDRUM-3 programme completion score and 0.596 with the DUNDRUM-4 recovery score. The Global Assessment of Function (GAF) score correlated inversely -0.650 with the DUNDRUM-3 programme completion score and -0.673 with the DUNDRUM-4 recovery score. All correlations with PANSS scales and GAF were statistically significant p < 0.001, n = 95.
Cross-validation with measures of risk and need for therapeutic security
The DUNDRUM-3 programme completion score correlated with the DUNDRUM-1 triage security score, a measure of need for therapeutic security (r = 0.346, p < 0.001) as did the DUNDRUM-4 recovery score (Spearman r = 0.444, p < 0.001).
The DUNDRUM-3 Programme Completion score correlated with the HCR-H score (the sum of the 10 'historical' or fixed risk factors) r = 0.480; with the HCR-C score (the sum of the five 'clinical' or current risk factors) r = 0.637; with the HCR-R score (the sum of the five 'risk' or future risk factors) r = 0.519; with the HCR-dynamic score (the sum of the 'C' and 'R' risk factors) r = 0.629 and with the HCR-20 total score r = 0.686 (all significant p < 0.001, n = 95).
The DUNDRUM-4 Recovery score correlated with the HCR-20 H sub-scale r = 0.446 and with the HCR-C score r = 0.731; with the HCR-R r = 0.533; with the HCR-dynamic items (C and R combined) r = 0.704; and with the HCR-20 total score r = 0.713 (all significant p < 0.001, n = 95). Because the fifth item of the DUNDRUM-4 recovery score is itself strongly dependent on the dynamic items of the HCR-20, a score was calculated for the other five of the DUNDRUM-4 recovery items only. This correlated with the HCR-H score r = 0.447; with the HCR-C score r = 0.725; with the HCR-R score r = 0.519; with the HCR-dynamic score r = 0.694; and with the HCR-20 total score r = 0.705 (all significant p < 0.001, n = 95), the omission making little difference.
The DUNDRUM-3 Programme Completion score correlated with the S-RAMM Background (historical, fixed) score r = 0.263 (p = 0.05); with the S-RAMM Current score r = 0.529; with the S-RAMM Future score 0.451; with the S-RAMM dynamic score (the sum of the S-RAMM current and future scores) r = 0.553; and with the S-RAMM total score r = 0.556 (all significant p < 0.001 except where indicated, n = 95).
The DUNDRUM-4 Recovery score correlated with the S-RAMM background score r = 0.197 (not significant); with the S-RAMM Current score r = 0.613; with the S-RAMM Future score r = 0.609; with the S-RAMM dynamic score r = 0.702; and with the S-RAMM total score r = 0.628 (all significant p < 0.001, n = 95 except where indicated).
Cross-Correlation With the CANFOR, a Measure of Met, Unmet and Total Need
Using the CANFOR, The DUNDRUM-3 programme completion score did not correlate significantly with the patient self-rated met needs (Spearman r = -0.11, NS), it did correlate with the patient self-rated unmet needs (r = 0.33, p = 0.002) and did not correlate with the patient rated total needs (r = 0.114, NS). For staff ratings, met needs did not correlate significantly with the DUNDRUM-3 programme completion score (r = 0.09, NS) but the DUNDRUM-3 did correlate with unmet needs r = 0.50, (p < 0.001) and total needs r = 0.36 (p < 0.001).
Comparing the CANFOR and the DUNDRUM-4 recovery score, patient self-ratings for met need did not correlate (r = -0.182, NS), patient rated unmet needs correlated modestly (r = 0.253, p = 0.019) while patient rated total needs did not correlate (r = 0.019, NS). Staff ratings of met need did not correlate with the DUNDRUM-4 score (r = -0.022, NS), though staff-rated unmet need correlated 0.501 (p < 0.001) while staff-rated total need correlated weakly (r = 0.238, p = 0.02).
Leave
Patients were divided into those who had no leave outside the hospital, those who had leave outside the hospital only when accompanied by staff and those who had unaccompanied leave outside the hospital. Because the fourth item in the DUNDRUM-4 recovery scale is largely determined by the level of leave, this was recalculated for the five other items only - referred to here as the DUNDRUM-4 RL score.
Table shows that the DUNDRUM-3 programme completion score was significantly lower for those who were allowed unaccompanied leave (ANOVA F = 38.1, df = 2, p < 0.001). Bonferroni post-hoc tests for multiple comparisons showed that those with unaccompanied leave had significantly lower scores than those with no leave or accompanied leave. This was also true for the DUNDRUM-4 recovery score (ANOVA F = 76.8, p < 0.001), post hoc tests showed that those with unaccompanied leave and accompanied leave both had significantly lower scores that those who had no leave p < 0.001 and p = 0.014, and held also when the leave item was excluded - DUNDRUM-4 RL, (ANOVA F = 56.6, df = 2, p < 0.001) post hoc tests demonstrated that those with unaccompanied leave had lower scores than those with accompanied leave (p < 0.001) or no leave (p < 0.001) while those with accompanied leave also had lower scores than those with no leave (p = 0.009).
| Table 1DUNDRUM-3 and DUNDRUM-4 according to level of leave outside hospital. |
Stratification along the recovery pathway - clusters
Because the women's unit is not part of the same recovery pathway as the arrangement of wards and units providing for men, the arrangement of wards into three clusters (acute & high secure, medium secure and pre-discharge) refers only to the 87 male patients. Table shows that the DUNDRUM-3 programme completion score was significantly different when each of the three stages were compared with each other (ANOVA F = 45.9, df = 2, p < 0.001, Bonferroni post hoc tests pre-discharge significantly less than acute/high secure p < 0.001 and medium secure p < 0.001, medium secure significantly less than acute/high secure p < 0.05). The DUNDRUM-4 recovery score was significantly lower only for those in the pre-discharge cluster (ANOVA F = 66.8, df = 2, p < 0.001, post-hoc test pre-discharge less than medium < 0.001 and acute/high secure p < 0.001).
| Table 2DUNDRUM-3 and DUNDRUM-4 according to place in the recovery pathway |
Stratification along the recovery pathway - by units
Table shows that static measures such as the DUNDRUM-1 triage security score, the HCR-20 'H' score (sum of historical items) and S-RAMM 'B' score (sum of background items) differ between units to a limited extent, with no clear pattern other than the accumulation of those with the highest fixed historical risk profile or risk factors in the intensive care unit while the pre-discharge units accumulate those with lower scores. The dynamic risk scores for the HCR-20 and S-RAMM present a clearer pattern of stratification from intensive care and admission units to pre-discharge. The strongest and most consistent stratification was found for the DUNDRUM-3 programme completion (ANOVA F = 45.9, df = 6, p < 0.001) and DUNDRUM-4 recovery scores (ANOVA F = 33.9, df = 6, p < 0.001) with falling scores from high secure/intensive care through medium secure units to low secure, pre-discharge and community high support.
| Table 3Cross-sectional stratification of patients along the recovery pathway - DUNDRUM-1 triage security, DUNDRUM-3 programme completion, DUNDRUM-4 recovery, HCR-20 historical (fixed), HCR-20 dynamic ('clinical' and 'risk' items), S-RAMM background (fixed) and (more ...) |
Bonferroni post hoc tests show that for the DUNDRUM-1, only the intensive care and the pre-discharge/community groups differed significantly (p = 0.021). For the DUNDRUM-3 and DUNDRUM-4, the low secure rehab and pre-discharge/community groups differed significantly from all other groups and from each other. For HCR-H, the medium secure unit 1 differed from the pre-discharge and community group p < 0.05. For HCR-dynamic the intensive care unit had a significantly higher mean score than all other units except the long term low secure unit, the low secure rehab unit was significantly lower than the intensive care unit, male medium secure unit 2 and the long term low secure unit, while the pre-discharge/community group was lower than all other units except the low secure rehab unit. S-RAMM dynamic scores were significantly lower in the pre-discharge/community group than for any other unit and the low secure rehab unit was significantly lower than the intensive care unit.
Table shows that the Global Assessment of Function (GAF) increases progressively from the intensive care and admission units through medium secure and low secure to pre-discharge and community units (ANOVA F = 12.0, p < 0.001). PANSS positive, PANSS negative, PANSS general and PANSS total scores also stratified, though less consistently. Table also shows that for the CANFOR, staff ratings of unmet need differed significantly across the recovery pathway as expected, (F = 5.9, p < 0.001) but neither staff-rated met needs nor staff-rated total needs differed significantly. Patient self-rated needs, met, unmet and total did not differ significantly.
| Table 4Cross-sectional stratification of patients along the recovery pathway - global function, symtoms and Camberwell Assessment of Need, forensic version (CANFOR). |
Bonferroni post hoc tests show that for the GAF, the pre-discharge/community group had significantly higher scores than all other units except the male low secure rehab unit while the intensive care unit had significantly lower scores than all but the admission high secure and medium secure unit 1. The PANSS positive score was significantly higher when the intensive care unit was compared with the low secure rehab and pre-discharge/community groups while the pre-discharge/community group had lower scores than the intensive care unit and the medium secure unit 1. PANSS negative scores were lower for the pre-discharge/community group than for the intensive care unit, admission/high secure unit, medium secure unit 1 and long term low secure unit. For PANSS general score, the pre-discharge/community group had a lower mean score than the intensive care unit or the medium secure unit 1. PANSS total score was higher for the intensive care unit than for the male low secure rehab and pre-discharge/community units while the pre-discharge and community group had a lower mean PANSS total score than the intensive care unit and the medium secure unit 1. CANFOR staff unmet needs were greater for medium secure unit 1 than the low secure rehab unit, the intensive care unit had a higher score than the low secure rehab unit and the pre-discharge/community group and the pre-discharge/community group had a lower mean score than the intensive care unit and medium secure unit 1.
DUNDRUM-3 and DUNDRUM-4 Individual Items and Proxy Outcomes
Tables and show that each item of the DUNDRUM-3 programme completion instrument and DUNDRUM-4 recovery instrument differed significantly across the recovery pathway clusters and according to the level of leave allowed at the time the ratings were made. Note that for level of leave, the DUNDRUM-4 recovery item 4 'leave' has an extremely high statistical significance because the definition makes this almost a circular measure.
| Table 5Item to outcome: DUNDRUM-3 and DUNDRUM-4 according to level of leave |
| Table 6Item to Outcome: DUNDRUM-3 and DUNDRUM-4 according to place in the recovery pathway |