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Nucleic Acids Res. 1986 June 11; 14(11): 4683–4690.
PMCID: PMC311474

A new method for predicting signal sequence cleavage sites.


A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.

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