A new method for predicting signal sequence cleavage sites.

Nucleic Acids Res. 1986 June 11; 14(11): 4683–4690.

PMCID: PMC311474

A new method for predicting signal sequence cleavage sites.

G von Heijne

See the article"The Zebrafish Secretome" in Zebrafish, volume 5 on page 131.

This article has been cited by other articles in PMC.

Abstract

A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.

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