PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of narLink to Publisher's site
 
Nucleic Acids Res. Jan 25, 1992; 20(2): 295–301.
PMCID: PMC310369
A new rRNA processing mutant of Saccharomyces cerevisiae.
L Lindahl, R H Archer, and J M Zengel
Department of Biology, University of Rochester, NY 14627.
Abstract
We have identified from a collection of temperature sensitive yeast mutants strains which fail to process rRNA normally. Characterization of one such mutant is reported here. This strain accumulates increased amounts of the 35S primary transcript, '24S' molecules extending from the transcription start site to the 5.8S region, and two classes of 5.8S rRNA with 5' extensions of 7 and 149 bases, respectively. We show that this pleiotropic change in the rRNA processing pattern is due to a single mutation. Possible models for the function of the mutated gene are discussed.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.5M), or click on a page image below to browse page by page.
Articles from Nucleic Acids Research are provided here courtesy of
Oxford University Press