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Nucleic Acids Res. Aug 11, 1994; 22(15): 3151–3154.
PMCID: PMC310289
LRG1 is expressed during sporulation in Saccharomyces cerevisiae and contains motifs similar to LIM and rho/racGAP domains.
L Müller, G Xu, R Wells, C P Hollenberg, and W Piepersberg
German Cancer Research Center, Heidelberg.
We here report the sequence of a yeast gene LRG1 whose deduced amino acid sequence contains sequence motifs similar to LIM domain proteins in the amino-terminal, and to rho/rac GTPase activating proteins (rho/racGAP's) in the carboxy-terminal part. LRG1 expression is differentially regulated showing a peak of expression in sporulating cells. Gene disruption experiments indicate that the gene is not essential and may play a role during mating.
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