Papers of special note have been highlighted as:
• of interest
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67. Migliaccio I, Gutierrez M, Wu M-F, et al. PI3 kinase activation and response to trastuzumab or lapatinib in HER-2 overexpressing locally advanced breast cancer. Cancer Res (Meeting Abstracts) 2009;69:S34.
68. Wong KK, Fracasso PM, Bukowski RM, et al. A Phase I study with neratinib (HKI-272), an irreversible pan ErbB receptor tyrosine kinase inhibitor, in patients with solid tumors. Clin Cancer Res. 2009;15:2552–2558. [PubMed] 69. Burstein HJ, Sun Y, Dirix LY, et al. Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer. J Clin Oncol. 2010;28:1301–1307. [PubMed]
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71. Awada A, Dirix L, Beck J, et al. Safety and efficacy of neratinib (HKI-272) in combination with vinorelbine in ErbB2+ metastatic breast cancer. Cancer Res (Meeting Abstracts) 2009;69:S5095.
72. Saura C, Martin M, Moroose R, et al. benefits. Safety of neratinib (HKI-272) in combination with capecitabine in patients with solid tumors: a Phase 1/2 study. Cancer Res (Meeting Abstracts) 2009;69:S5108.
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104. Baselga J, De Jonge MJ, Rodon J, et al. A first-in-human Phase I study of BKM120, an oral pan-class I PI3K inhibitor, in patients (pts) with advanced solid tumors. J Clin Oncol (Meeting Abstracts) 2010;28:3003. [PubMed]
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106. Andre F, Campone M, Hurvitz SA, et al. Multicenter Phase I clinical trial of daily and weekly RAD001 in combination with weekly paclitaxel and trastuzumab in patients with HER2-overexpressing metastatic breast cancer with prior resistance to trastuzumab. J Clin Oncol (Meeting Abstracts) 2008;26:1003.
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