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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
From:
Clin Exp Metastasis. Author manuscript; available in PMC 2011 March 11.
Published in final edited form as:
Clin Exp Metastasis. 2010 March; 27(3): 173–184.
Published online 2010 March 26. doi: 10.1007/s10585-010-9316-1

Fig. 2

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Hill-Slope plots of the increased invasion-inhibitory potency of Ac-PHSCNGGK-MAP as compared with the Ac-PHSCN-NH2 peptide with naturally serum-free, selectively permeable basement membranes from sea urchin embryos as invasion substrates. Panel (a). Inhibition of serum–induced DU 145 invasion. Panel (b). Inhibition of serum–induced PC-3 invasion. Panel (c). Inhibition of Ac-PHSRN-NH2–induced, SF DU 145 invasion. Panel (d). Inhibition of Ac-PHSRN-NH2–induced, SF PC-3 invasion. X axes, log peptide concentration in nM; Y axes, mean percentages of invaded cells, relative to uninhibited, FBS– or PHSRN–stimulated controls (+/− SD). Black circles, Ac-PHSCNGGK-MAP; black triangles, Ac-PHSCN-NH2 peptide; black diamonds, Ac-HSPNCGGK-MAP; white circles, Ac-HSPNC-NH2 peptide; white squares, Ac-PHSCNGGK-Ova.

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