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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
From:
Science. Author manuscript; available in PMC 2011 March 7.
Published in final edited form as:
Science. 2001 April 27; 292(5517): 727–730.
doi: 10.1126/science.1059108

Table 1

Susceptibility of mice lacking Bax, Bak, or both to anti-Fas injection. Mice were injected intravenously with 0.5 µg of monoclonal antibody to Fas (Jo2, Pharmingen) per gram of body weight and killed when moribund or observed for up to 24 hours. Mean survival time in hours ± 1 SD is shown for mice that died.

GenotypeDead/
injected
Mean survival
(hours)
Bak−/−9/135.2 ± 1.7
Bak+/− or +/+9/146.0 ± 2.7
Bax−/−7/103.8 ± 1.2
Bax+/− or +/+13/132.6 ± 1.9
Bax−/−, Bak−/−0/3(killed after 9 hours)