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BMJ Case Rep. 2010; 2010: bcr12.2009.2528.
Published online 2010 April 29. doi:  10.1136/bcr.12.2009.2528
PMCID: PMC3047551
Reminder of important clinical lesson

Paroxetine and neonatal withdrawal syndrome

Abstract

We report a case of neonatal withdrawal syndrome after in utero exposure to paroxetine 20 mg/day. The infant’s symptoms, such as poor neonatal adaptation, respiratory distress, decerebrate posturing, irritability and tremors, commenced soon after birth and persisted for 5 days. All neonates exposed to antidepressants, particularly serotonin reuptake inhibitors (SSRIs), during the last trimester should be followed-up closely for adverse symptoms.


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