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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
From:
JACC Cardiovasc Imaging. Author manuscript; available in PMC 2011 March 1.
Published in final edited form as:
JACC Cardiovasc Imaging. 2010 March; 3(3): 266–274.
doi: 10.1016/j.jcmg.2009.10.012

Table 4

Association of Obesity Measures With LV Parameters by Sex After Adjustment for Risk Factors in MESA Participants With CMR (N = 5,004)

Women
Men
LV ParameterObesity MeasureSlope (per 10-Unit Change
in Obesity Measure)
p ValueSlope (per 10-Unit Change
in Obesity Measure)
p Valuep Value for
Sex Interaction
LV mass (g)BMI range (kg/m2)
<2521.9<0.00144.2<0.001<0.001
25–3027.0<0.00126.1<0.001
>3015.4<0.00127.6<0.001
FM (kg)5.7<0.0016.9<0.0010.15
LBM (kg)19.1<0.00118.6<0.0010.36
WHR*48.3<0.00169.4<0.001<0.001
LV volume (ml)BMI range (kg/m2)
<2521.7<0.00127.2<0.0010.35
25–3019.1<0.00113.00.001
>3013.4<0.00110.40.008
FM (kg)3.4<0.001−2.10.052<0.001
LBM (kg)21.7<0.00123.9<0.0010.10
WHR*12.80.03825.90.0130.38
M/V ratio (g/ml)BMI range (kg/m2)
<250.010.9970.100.024<0.001
25–300.050.0510.080.021
>300.010.4970.090.004
FM (kg)0.02<0.0010.06<0.001<0.001
LBM (kg)−0.040.001−0.07<0.0010.45
WHR*0.32<0.0010.33<0.0010.74
Ejection fraction (%)BMI range (kg/m2)
<250.20.882.20.110.80
25–300.10.900.00.98
>30−1.00.06−0.70.47
FM (kg)−1.00.460.40.140.28
LBM (kg)−0.40.34−1.00.020.48
WHR*0.820.64−0.970.700.20
*Each slope corresponds to 1-unit change in WHR. All models are stratified by sex, and adjusted for age, race, systolic and diastolic blood pressures, use of antihypertensive medications, diabetes, cigarette smoking, total cholesterol, HDL, log triglycerides, use of lipid-lowering medication, family history of heart attack, heavy drinking, and intentional exercise in quartiles. Linear regression models examining associations between FM and LV parameters additionally adjusted for LBM.

LBM = lean body mass; M/V = mass to volume; other abbreviations as in Tables Tables11 and and22.