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BMJ Case Rep. 2010; 2010: bcr10.2009.2378.
Published online 2010 March 30. doi:  10.1136/bcr.10.2009.2378
PMCID: PMC3029984
Unexpected outcome (positive or negative) including adverse drug reactions

Sudden death due to medulloblastoma


Intracranial tumours can be accompanied with intracerebral and intracerebellar non-traumatic haemorrhage; in some cases, this might be their first clinical sign. We report a case of a man who suffered sudden death due to medulloblastoma, with intratumoral haemorrhage; his tumour had a hemispheric cerebellar positioning. The cerebral oedema seen at autopsy reflected the immediate cessation of cerebral vascular circulation, leading to sudden death. Acute obstructive hydrocephaly is a mechanism widely known in the literature for causing sudden death.

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