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BMJ Case Rep. 2010; 2010: bcr0120102679.
Published online 2010 July 22. doi:  10.1136/bcr.01.2010.2679
PMCID: PMC3029916
Findings that shed new light on the possible pathogenesis of a disease or an adverse effect

Antenatal management of pulmonary hyperplasia (congenital cystic adenomatoid malformation)


A 26-year-old lady was seen in antenatal clinic. Her anomaly scan at 20 weeks showed significant fetal abdominal ascites and an enlarged echo bright right lung with cardiac displacement. These findings were consistent with recognised type III congenital cystic adenomatoid malformation (CCAM). An induction of labour was undertaken at 32 weeks' gestation due to increasing maternal morbidity. Labour was complicated by abdominal dystocia and a fetal paracentesis was performed, draining 800 ml. A bradycardia developed and the baby was ultimately stillborn. Post mortem examination the right lower lobe bronchus was atretic. The features were typical of those traditionally described as type III CCAM, but in the context of bronchial atresia, are better described as pulmonary hyperplasia.

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