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BMJ Case Rep. 2010; 2010: bcr0820092216.
Published online 2010 January 13. doi:  10.1136/bcr.08.2009.2216
PMCID: PMC3029862
Unusual association of diseases/symptoms

Hypocalcaemia, long QT interval and atrial arrhythmias


Calcium has diverse roles in neuromuscular mechanisms. Within the cardiovascular system, hypocalcaemia is known to both impair myocardial contractility and prolong the QT interval, predisposing to ventricular arrhythmias. We present a case of chronic hypocalcaemia with prolonged QT interval associated with an atrial arrhythmia. Recent studies of congenital long QT syndrome suggest there is also a predisposition to atrial arrhythmias. Our case raises the hypothesis that acquired causes of long QT cause similar repolarisation abnormalities that predispose to atrial arrhythmias.

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