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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
 
BMJ Case Rep. 2010; 2010: bcr01.2009.1420.
Published online Mar 15, 2010. doi:  10.1136/bcr.01.2009.1420
PMCID: PMC3029549
Unexpected outcome (positive or negative) including adverse drug reactions
Ischaemic stroke in a patient on sunitinib
Maire Therese Lonergan,1 Feargal Kellehar,2 Raymond McDermott,2 and Ronan Collins1
1Adelaide & Meath Hospital, Stroke Unit and Department of Gerontology, Tallaght, Dublin, D24, Ireland
2Adelaide and Meath Hospital, Oncology, Tallaght, Dublin, D24, Ireland
Correspondence to Ronan Collins, Ronan.Collins2/at/amnch.ie
Abstract
Concerns have been raised about possible theoretical risk of thrombosis and bleeding with sunitinib (anti-vascular endothelial cell growth factor agent) therapy used for treatment of metastatic renal cell carcinoma. We present the first case of stroke in an older man with metastatic renal cell carcinoma, on sunitinib therapy.
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