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BMJ Case Rep. 2010; 2010: bcr11.2009.2475.
Published online 2010 March 8. doi:  10.1136/bcr.11.2009.2475
PMCID: PMC3029368
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Dynamic renogram with 99mTc DTPA in patient with adult polycystic kidney disease


A 40-year-old man presented with chronic renal failure for follow-up on differential renal function.

15 mCi of 99mTc DTPA were injected and flow phase, perfusion and excretion phases were obtained and examined. There was delayed radiotracer excretion in keeping with reduced glomerular filtration rate. The delayed images demonstrated enlarged, distorted renal collecting systems bilaterally (tracer accumulation wthin peripelvic cysts) (fig 1). Selected axial CT image through the abdomen was also available for anatomic correlation and demonstrated severe enlargement of both kidneys due to multiple cysts (fig 2).

Figure 1
Figure 2
Axial computed tomography image through the kidneys.


Competing interests: None.

Further reading

1. Dubovsky EV, Russell CD. Quantitation of renal function with glomerular and tubular agents. Semin Nucl Med 1982; 12: 308–329 [PubMed]
2. Klopper JF, Hauser W, Atkins HL, et al. Evaluation of 99mTc-DTPA for the measurement of glomerular filtration rate. J Nucl Med 1972; 13: 107–10 [PubMed]
3. Babu R, Basarge N, Ahlawat R, et al. Prediction of functional outcome in poorly functioning kidneys with unilateral pelviureteric junction obstruction: analysis of clinical features and lsotope renography. Indian J Urol 1996; 12: 65–70

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