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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
 
BMJ Case Rep. 2010; 2010: bcr0120102689.
Published online Oct 12, 2010. doi:  10.1136/bcr.01.2010.2689
PMCID: PMC3028444
Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Auditory neuropathy associated with postnatally acquired cytomegalovirus infection in a very preterm infant
W Baerts1 and H L M (Irma) van Straaten2
1Department of Neonatology, Utrecht University Hospital/Wilhelmina Children's Hospital, Utrecht, The Netherlands
2Department of Neonatology, Isala Clinics, Zwolle, The Netherlands
Correspondence to H L M van Straaten, h.l.m.van.straaten/at/isala.nl
Abstract
Neurosensory hearing loss is a well-known complication of antenatally acquired cytomegalovirus (CMV) infection. We here report an infant who developed auditory neuropathy after a postnatally acquired CMV infection. Infection probably occurred through ingestion of infected breast milk. Following a cochlear implant, there is normal language perception and a mildly delayed language expression at age 4. We speculate that the long-term effects of perinatal CMV infections are more dependent on the postconceptional age at which infection occurs than on whether the infection occurs antenatally or postnatally. An early acquired neonatal CMV infection in very preterm infants may therefore have long-term neurological sequelae, including auditory deficits.
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