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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
BMJ Case Rep. 2010; 2010: bcr1020092405.
Published online Oct 8, 2010. doi:  10.1136/bcr.10.2009.2405
PMCID: PMC3028032
Unexpected outcome (positive or negative) including adverse drug reactions
Accelerated avascular necrosis after single intra-articular injection of corticosteroid into the hip joint
A M Kassam
Department of Trauma and Orthopaedics, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK
Correspondence to A M Kassam, akassam/at/
Avascular necrosis (AVN) involves destruction of the hip joint. Long-term use of steroids has been shown to cause AVN. This article presents a case of intra-articular injection of steroid causing a rapid onset of AVN in the hip joint. Bone histology at time of total hip replacement showed evidence of AVN and no evidence of infection.
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