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BMJ Case Rep. 2010; 2010: bcr1020092405.
Published online 2010 October 8. doi:  10.1136/bcr.10.2009.2405
PMCID: PMC3028032
Unexpected outcome (positive or negative) including adverse drug reactions

Accelerated avascular necrosis after single intra-articular injection of corticosteroid into the hip joint


Avascular necrosis (AVN) involves destruction of the hip joint. Long-term use of steroids has been shown to cause AVN. This article presents a case of intra-articular injection of steroid causing a rapid onset of AVN in the hip joint. Bone histology at time of total hip replacement showed evidence of AVN and no evidence of infection.

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