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Logo of bmjcrInstructions for authorsCurrent ToCBMJ Case Reports
BMJ Case Rep. 2010; 2010: bcr0520091825.
Published online Nov 23, 2010. doi:  10.1136/bcr.05.2009.1825
PMCID: PMC3027866
Reminder of important clinical lesson
Late onset of subfoveal choroidal neovascularisation following cerebral radiotherapy
Abdul-Jabbar Ghauri,1 Mohammed Musadiq,2 Ying Sha,1 and Samer Elsherbiny1
1Department of Ophthalmology, Birmingham and Midlands Eye Centre, Birmingham, UK
2Department of Ophthalmology, University Hospital of North Staffordshire, Stoke on Trent, UK
Correspondence to Abdul-Jabbar Ghauri, aj.ghauri/at/
A report of choroidal neovascularisation (CNV) associated with radiation retinopathy. A 43-year-old Caucasian man presented with a 4-week history of sudden loss of central vision in the left eye, 8.5 years following radical radiotherapy for left tempero-parietal anaplastic astrocytoma. His visual acuity was 6/6 in the right eye and 6/60 in the left eye. Ophthalmoscopy of the left eye showed central macular pigmented area surrounded by subretinal fluid, haemorrhage and exudates. Fundus fluorescein angiography revealed left subfoveal CNV with surrounding macular oedema and peripheral retinal ischaemia. Radiation retinopathy associated CNV is a late ocular complication of cerebral radiotherapy. It should be investigated as a possible aetiology of severe visual loss in long-term survivors of cerebral tumours who have previously received radiotherapy.
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