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BMJ Case Rep. 2010; 2010: bcr0420102873.
Published online 2010 September 13. doi:  10.1136/bcr.04.2010.2873
PMCID: PMC3027727
Unusual association of diseases/symptoms

Cleft palate, arachnoid cyst and posterior urethral valve


A 5-month-old infant presented with cleft palate, febrile urinary tract infection and abnormal movements. His urinary stream was poor and investigations revealed posterior urethral valve and grade V vesicoureteric reflux. This baby was investigated for seizure activity and on MRI of the brain was found to have a large arachnoid cyst, splaying the occipital horns and compressing the posterior aspect of third ventricle leading to dilatation of the ventricles.

This seems to be a very unusual coexistence of three abnormalities in one patient for which no plausible explanation can be given. It appears to be a chance finding.

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